Lsm10

Summary

Gene Symbol: Lsm10
Description: Lsm10
Alias: CG12938, Dmel\CG12938, dLsm10, Lsm10, CG12938-PA, Lsm10-PA
Species: fruit fly

Top Publications

  1. Azzouz T, Schumperli D. Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster. RNA. 2003;9:1532-41 pubmed
    ..Immunoprecipitation studies in Drosophila S2 cells indicate that the Drosophila Lsm10 and Lsm11 orthologs (dLsm10 and dLsm11) associate with each other and with Sm B, but not with Sm D1 and D2...
  2. Liu J, Murphy C, Buszczak M, Clatterbuck S, Goodman R, Gall J. The Drosophila melanogaster Cajal body. J Cell Biol. 2006;172:875-84 pubmed
    ..melanogaster. The identification of these nuclear bodies now permits a broad range of questions to be asked about CB structure and function in a genetically tractable organism. ..
  3. Lee L, Davies S, Liu J. The spinal muscular atrophy protein SMN affects Drosophila germline nuclear organization through the U body-P body pathway. Dev Biol. 2009;332:142-55 pubmed publisher
    ..Taken together, our results suggest that SMN is required for the functional integrity of the U body-P body pathway, which in turn is important for maintaining proper nuclear architecture. ..
  4. Godfrey A, White A, Tatomer D, Marzluff W, Duronio R. The Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in development. RNA. 2009;15:1661-72 pubmed publisher
    ..U7 snRNP contains two like-Sm proteins, Lsm10 and Lsm11, which replace SmD1 and SmD2 in the canonical heptameric Sm protein ring that binds spliceosomal snRNAs...
  5. Bulchand S, Menon S, George S, Chia W. Muscle wasted: a novel component of the Drosophila histone locus body required for muscle integrity. J Cell Sci. 2010;123:2697-707 pubmed publisher
    ..We speculate that mute regulates terminal muscle differentiation possibly through heterochromatic reorganisation. ..
  6. Liu J, Gall J. U bodies are cytoplasmic structures that contain uridine-rich small nuclear ribonucleoproteins and associate with P bodies. Proc Natl Acad Sci U S A. 2007;104:11655-9 pubmed
    ..The identification of U bodies provides an opportunity to correlate specific biochemical steps of snRNP biogenesis with structural features of the cytoplasm. ..

Scientific Experts