Genomes and Genes
Gene Symbol: Lsd-1
Description: Lipid storage droplet-1
Alias: CG10374, DmPLIN1, Dmel\CG10374, LSD-1, LSDP1, Lsd1, Lsdp1, PLIN1, lsd1, plin1, lipid storage droplet-1, CG10374-PA, CG10374-PB, CG10374-PC, CG10374-PD, Lsd-1-PA, Lsd-1-PB, Lsd-1-PC, Lsd-1-PD, lipid storage droplet protein 1, lipid storage droplets surface binding protein, perilipin
Species: fruit fly
- Beller M, Bulankina A, Hsiao H, Urlaub H, Jackle H, Kühnlein R. PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila. Cell Metab. 2010;12:521-32 pubmed publisher..In mammals, members of the evolutionarily conserved PERILIPIN protein family are associated with the lipid droplet surface and participate in lipid homeostasis...
- Eliazer S, Palacios V, Wang Z, Kollipara R, Kittler R, Buszczak M. Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells. PLoS Genet. 2014;10:e1004200 pubmed publisher..Loss of the highly conserved histone demethylase Lsd1 in Drosophila escort cells results in increased BMP signaling outside the cap cell niche and an expanded germline ..
- Tsuda Sakurai K, Seong K, Horiuchi J, Aigaki T, Tsuda M. Identification of a novel role for Drosophila MESR4 in lipid metabolism. Genes Cells. 2015;20:358-65 pubmed publisher..These results suggest that MESR4 acts as an important upstream regulator of energy homeostasis. ..
- Arrese E, Rivera L, Hamada M, Mirza S, Hartson S, Weintraub S, et al. Function and structure of lipid storage droplet protein 1 studied in lipoprotein complexes. Arch Biochem Biophys. 2008;473:42-7 pubmed publisher..Several proteins surrounding the LDs have been implicated in TG homeostasis such as mammalian perilipin A and insect lipid storage proteins (Lsd)...
- Thiel K, Heier C, Haberl V, Thul P, Oberer M, Lass A, et al. The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage. J Cell Sci. 2013;126:2198-212 pubmed publisher..The results indicate that we identified the first members of a novel and evolutionarily conserved family of lipid storage regulators, which are also required to properly position LDs within cells. ..