Gene Symbol: levy
Description: levy
Alias: BcDNA:RH03295, CG17280, COX6A, COXD, COXE, Cox6a, Dmel\CG17280, VIa, levy, CG17280-PA, CG17280-PB, cytochrome c oxidase VIa, cytochrome c oxidase polypeptide VIA, cytochrome c oxidase subunit 6A, levy-PA, levy-PB
Species: fruit fly

Top Publications

  1. Liu W, Gnanasambandam R, Benjamin J, Kaur G, Getman P, Siegel A, et al. Mutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in Drosophila. Genetics. 2007;176:937-46 pubmed
    ..Here we report mutations in a gene (designated levy) that codes for subunit VIa of cytochrome c oxidase (COX)...
  2. Sage B, Jones J, Holmes A, Wu M, Csink A. Sequence elements in cis influence heterochromatic silencing in trans. Mol Cell Biol. 2005;25:377-88 pubmed
    ..Intriguingly, this region encompasses the upstream regions of two divergently transcribed genes and contains a sequence motif that may bind BEAF, a protein involved in delimiting chromatin boundaries. ..
  3. Kemppainen K, Rinne J, Sriram A, Lakanmaa M, Zeb A, Tuomela T, et al. Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency. Hum Mol Genet. 2014;23:2078-93 pubmed publisher
    ..These findings confirm the potential utility of alternative respiratory chain enzymes as tools to combat mitochondrial disease, while indicating important limitations thereof. ..
  4. Szuplewski S, Terracol R. The cyclope gene of Drosophila encodes a cytochrome c oxidase subunit VIc homolog. Genetics. 2001;158:1629-43 pubmed
    ..A search in the Genome Annotation Database of Drosophila revealed the absence of subunit VIIb and the presence of 9 putative nuclear cytochrome c oxidase subunits with high identity scores when compared to the 10 human subunits. ..
  5. Brown A, Baumbach J, Cook P, Ligoxygakis P. Short-term starvation of immune deficient Drosophila improves survival to gram-negative bacterial infections. PLoS ONE. 2009;4:e4490 pubmed publisher
    ..Our results show that NO release through STS may reflect an evolutionary conserved process. Moreover, STS could be explored to address immune phenotypes related to infection and may offer ways to boost natural immunity. ..
  6. Porcelli D, Oliva M, Duchi S, Latorre D, Cavaliere V, Barsanti P, et al. Genetic, functional and evolutionary characterization of scox, the Drosophila melanogaster ortholog of the human SCO1 gene. Mitochondrion. 2010;10:433-48 pubmed publisher