Gene Symbol: Karybeta3
Description: Karyopherin beta 3
Alias: CG1059, Dmel\CG1059, Karbeta3, Kary-beta3, l(3)82CDd, l(3)j3A4, l(3)j7E8, karyopherin beta 3, CG1059-PA, CG1059-PB, Karybeta3-PA, Karybeta3-PB, karyopherin beta, karyopherin-beta3, lethal (3) 82CDd
Species: fruit fly
Colas J, Launay J, Maroteaux L. Maternal and zygotic control of serotonin biosynthesis are both necessary for Drosophila germband extension. Mech Dev. 1999;87:67-76 pubmed
..Together, these findings provide additional support for the notion that serotonin, acting through the 5-HT(2Dro) receptor, is necessary for proper gastrulation. ..
Colas J, Launay J, Vonesch J, Hickel P, Maroteaux L. Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila. Mech Dev. 1999;87:77-91 pubmed
Clyne P, Brotman J, Sweeney S, Davis G. Green fluorescent protein tagging Drosophila proteins at their native genomic loci with small P elements. Genetics. 2003;165:1433-41 pubmed
..This technology allows the generation of GFP-tagged reagents on a genome-wide scale with diverse potential applications. ..
Schaerlinger B, Launay J, Vonesch J, Maroteaux L. Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation. Dev Dyn. 2007;236:991-9 pubmed
Hayward D, Wakefield J. Chromatin-mediated microtubule nucleation in Drosophila syncytial embryos. Commun Integr Biol. 2014;7:e28512 pubmed publisher
Tsubouchi A, Caldwell J, Tracey W. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Curr Biol. 2012;22:2124-34 pubmed publisher
..These cells show physiological responses to force. Ion channels in several force-sensing gene families are required for behavioral sensitivity to touch and for the formation of the actin-rich sensory filopodia. ..
Nahm M, Lee M, Parkinson W, Lee M, Kim H, Kim Y, et al
. Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization. Neuron. 2013;77:680-95 pubmed publisher
Tiebe M, Lutz M, De La Garza A, Buechling T, Boutros M, Teleman A. REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1. Dev Cell. 2015;33:272-84 pubmed publisher
..In vivo functional analysis using knockout flies reveals that REPTOR and REPTOR-BP play critical roles in maintaining energy homeostasis and promoting animal survival upon nutrient restriction. ..