Gene Symbol: IntS11
Description: Integrator 11
Alias: CG1972, Dmel\CG1972, Int11, dRC-68, integrator 11, CG1972-PA, IntS11-PA
Species: fruit fly

Top Publications

  1. Yang X, Burch B, Yan Y, Marzluff W, Dominski Z. FLASH, a proapoptotic protein involved in activation of caspase-8, is essential for 3' end processing of histone pre-mRNAs. Mol Cell. 2009;36:267-78 pubmed publisher
    ..These results demonstrate that FLASH is an essential factor required for 3' end maturation of histone mRNAs in both vertebrates and invertebrates and suggest a potential link between this process and apoptosis. ..
  2. Chen J, Waltenspiel B, Warren W, Wagner E. Functional analysis of the integrator subunit 12 identifies a microdomain that mediates activation of the Drosophila integrator complex. J Biol Chem. 2013;288:4867-77 pubmed publisher
    ..Collectively, these results identify an unexpected interaction between the largest and smallest integrator subunits that is essential for the 3' end formation of Drosophila snRNA. ..