Gene Symbol: inaE
Description: inactivation no afterpotential E
Alias: CG11096, CG11102, CG11104, CG15761, CG32630, CG33174, DAGL, Dmel\CG33174, EP(X)1101, inactivation no afterpotential E, CG33174-PA, CG33174-PD, CG33174-PE, CG33174-PF, CG33174-PG, CG33174-PH, diacylglycerol lipase, inaE-PA, inaE-PD, inaE-PE, inaE-PF, inaE-PG, inaE-PH
Species: fruit fly

Top Publications

  1. Leung H, Tseng Crank J, Kim E, Mahapatra C, Shino S, Zhou Y, et al. DAG lipase activity is necessary for TRP channel regulation in Drosophila photoreceptors. Neuron. 2008;58:884-96 pubmed publisher
    ..A crucial enzyme in the understanding of this process is likely to be DAG lipase (DAGL). However, DAGLs that might fulfill this role have not been previously identified in any organism...
  2. McPartland J, Matias I, Di Marzo V, Glass M. Evolutionary origins of the endocannabinoid system. Gene. 2006;370:64-74 pubmed
    ..Our methods identified fewer orthologs than did automated annotation systems, such as HomoloGene. Phylogenetic profiles, nonorthologous gene displacement, functional convergence, and coevolution are discussed. ..
  3. Anishkin A, Loukin S, Teng J, Kung C. Feeling the hidden mechanical forces in lipid bilayer is an original sense. Proc Natl Acad Sci U S A. 2014;111:7898-905 pubmed publisher
    ..Today, overt or covert mechanical forces govern cell biological processes and produce sensations. At the genesis, a bilayer's response to osmotic force is likely among the first senses to deal with the capricious primordial sea. ..
  4. Lin Y, Chen Y, Kao T, Lin Y, Hsu T, Wu Y, et al. Diacylglycerol lipase regulates lifespan and oxidative stress response by inversely modulating TOR signaling in Drosophila and C. elegans. Aging Cell. 2014;13:755-64 pubmed publisher
    ..DAG is metabolized to either PA via the action of DAG kinase or 2-arachidonoyl-sn-glycerol by diacylglycerol lipase (DAGL)...
  5. Murali T, Pacifico S, Finley R. Integrating the interactome and the transcriptome of Drosophila. BMC Bioinformatics. 2014;15:177 pubmed publisher
    ..This organization implies that tissue or stage specific networks can be best identified from interactome data by using filters designed to include both ubiquitously expressed and specifically expressed genes and proteins. ..