Gene Symbol: IleRS
Description: Isoleucyl-tRNA synthetase
Alias: Aats-ile, CG11471, Dmel\CG11471, IRS, l(3)00827, Isoleucyl-tRNA synthetase, CG11471-PA, CG11471-PC, CG11471-PD, IleRS-PA, IleRS-PC, IleRS-PD
Species: fruit fly

Top Publications

  1. Baumgartner S, Martin D, Chiquet Ehrismann R, Sutton J, Desai A, Huang I, et al. The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis. J Mol Biol. 1995;251:41-9 pubmed
    ..Of the vertebrate HEM family members, the mammalian Hem-1 gene is expressed only in cells of hematopoietic origin, while Hem-2 is preferentially expressed in brain, heart, liver and testis. ..
  2. Kerjan P, Cerini C, Semeriva M, Mirande M. The multienzyme complex containing nine aminoacyl-tRNA synthetases is ubiquitous from Drosophila to mammals. Biochim Biophys Acta. 1994;1199:293-7 pubmed
    ..These findings support the proposal according to which the multisynthetase complex is an idiosyncratic feature of all higher eukaryotic cells. ..
  3. Seshaiah P, Andrew D. WRS-85D: A tryptophanyl-tRNA synthetase expressed to high levels in the developing Drosophila salivary gland. Mol Biol Cell. 1999;10:1595-608 pubmed
    ..We also discuss the potential noncanonical activities of tryptophanyl-tRNA synthetase in immune response and regulation of cell growth. ..
  4. Wong S, Chen Y, Chan C, Chan C, Chan P, Chui Y, et al. In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila. Biochem Biophys Res Commun. 2005;337:720-9 pubmed
  5. Slack C, Somers W, Sousa Nunes R, Chia W, Overton P. A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions. BMC Genet. 2006;7:33 pubmed
    ..Taken together, these results demonstrate the value of mosaic screens in the identification of genes involved in neuroblast division. ..