HisRS

Summary

Gene Symbol: HisRS
Description: Histidyl-tRNA synthetase
Alias: Aats-his, CG6335, Dmel\CG6335, HRS, Harsl, l(1)G0165, l(1)G0358, Histidyl-tRNA synthetase, CG6335-PA, CG6335-PC, CG6335-PD, CG6335-PE, HisRS-PA, HisRS-PC, HisRS-PD, HisRS-PE
Species: fruit fly

Top Publications

  1. Seshaiah P, Andrew D. WRS-85D: A tryptophanyl-tRNA synthetase expressed to high levels in the developing Drosophila salivary gland. Mol Biol Cell. 1999;10:1595-608 pubmed
    ..We also discuss the potential noncanonical activities of tryptophanyl-tRNA synthetase in immune response and regulation of cell growth. ..
  2. Adolfsen B, Saraswati S, Yoshihara M, Littleton J. Synaptotagmins are trafficked to distinct subcellular domains including the postsynaptic compartment. J Cell Biol. 2004;166:249-60 pubmed
    ..In addition, the identification of a postsynaptic synaptotagmin suggests calcium-dependent membrane-trafficking functions on both sides of the synapse. ..
  3. Lotti F, Imlach W, Saieva L, Beck E, Hao L, Li D, et al. An SMN-dependent U12 splicing event essential for motor circuit function. Cell. 2012;151:440-54 pubmed publisher
    ..These findings directly link defective splicing of critical neuronal genes induced by SMN deficiency to motor circuit dysfunction, establishing a molecular framework for the selective pathology of SMA. ..
  4. Armstrong A, Laws K, Drummond Barbosa D. Adipocyte amino acid sensing controls adult germline stem cell number via the amino acid response pathway and independently of Target of Rapamycin signaling in Drosophila. Development. 2014;141:4479-88 pubmed publisher
    ..These studies reveal a new step in adipocyte-stem cell crosstalk. ..

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