Genomes and Genes
Gene Symbol: HipHop
Description: HP1-HOAP-interacting protein
Alias: BcDNA:RE10558, CG6874, Dmel\CG6874, HIPHOP, Hiphop, hiphop, l(3)neo26, HP1-HOAP-interacting protein, CG6874-PA, CG6874-PB, HP1 and HOAP-interacting protein, HP1-HOAP interacting protein, HipHop-PA, HipHop-PB, l(3)neo26, lethal (3) neo26
Species: fruit fly
- Cipressa F, Morciano P, Bosso G, Mannini L, Galati A, Raffa G, et al. A role for Separase in telomere protection. Nat Commun. 2016;7:10405 pubmed publisher..Finally, we find that siRNA-induced depletion of ESPL1, the Sse human orthologue, causes telomere dysfunction and HP1 level reduction in primary fibroblasts, highlighting a conserved role of Separase in telomere protection. ..
- Dubruille R, Marais G, Loppin B. Repeated evolution of testis-specific new genes: the case of telomere-capping genes in Drosophila. Int J Evol Biol. 2012;2012:708980 pubmed publisher..Here we review the case of such a new gene, which involves a telomere-capping gene family in Drosophila. hiphop and its testis-specific paralog K81 are critical for the protection of chromosome ends in somatic cells and male ..
- Raffa G, Cenci G, Ciapponi L, Gatti M. Organization and Evolution of Drosophila Terminin: Similarities and Differences between Drosophila and Human Telomeres. Front Oncol. 2013;3:112 pubmed publisher..that Drosophila telomeres are capped by the terminin complex, which includes the fast-evolving proteins HOAP, HipHop, Moi, and Ver...
- Vedelek B, BlastyÃ¡k A, Boros I. Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. PLoS ONE. 2015;10:e0142771 pubmed publisher..melanogaster Drosophila Telomere Loss and D. yakuba Verrocchio proteins does not preclude their stable interaction. ..
- Kurzhals R, Fanti L, Ebsen A, Rong Y, Pimpinelli S, Golic K. Chromosome Healing Is Promoted by the Telomere Cap Component Hiphop in Drosophila. Genetics. 2017;207:949-959 pubmed publisher..In addition, overexpression of the telomere cap component Hiphop increased the survival of somatic cells with broken chromosomes, while the cap component HP1 did not, and ..