Gene Symbol: heix
Description: heixuedian
Alias: 124/1, BG:DS02740.7, CG5876, Dmel\CG5876, ipa-6d, l(2)35Fc, l(2)k12401, heixuedian, CG5876-PA, heix-PA, lethal(2)35Fc
Species: fruit fly

Top Publications

  1. Reese M, Hartzell G, Harris N, Ohler U, Abril J, Lewis S. Genome annotation assessment in Drosophila melanogaster. Genome Res. 2000;10:483-501 pubmed
  2. Dawson I, Roth S, Artavanis Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol. 1995;129:725-37 pubmed
    ..Our data suggest that fzy function is required for normal cell cycle-regulated proteolysis that is necessary for successful progress through mitosis. ..
  3. Eberl D, Ren D, Feng G, Lorenz L, Van Vactor D, Hall L. Genetic and developmental characterization of Dmca1D, a calcium channel alpha1 subunit gene in Drosophila melanogaster. Genetics. 1998;148:1159-69 pubmed
    ..Those that do eclose have difficulty in fluid-filling of the wings. These studies show that this member of the calcium channel alpha1 subunit gene family plays a nonredundant, vital role in larvae and adults. ..
  4. Prokop A, Uhler J, Roote J, Bate M. The kakapo mutation affects terminal arborization and central dendritic sprouting of Drosophila motorneurons. J Cell Biol. 1998;143:1283-94 pubmed
    ..On the other, a specific type of sensory neuron (scolopidial neurons) shows defects in microtubule organization and detaches from its support cells. ..
  5. Willingham A, Keil T. A tissue specific cytochrome P450 required for the structure and function of Drosophila sensory organs. Mech Dev. 2004;121:1289-97 pubmed
  6. Vos M, Esposito G, Edirisinghe J, Vilain S, Haddad D, Slabbaert J, et al. Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. Science. 2012;336:1306-10 pubmed publisher
    ..We identified Drosophila UBIAD1/Heix as a modifier of pink1, a gene mutated in Parkinson's disease that affects mitochondrial function...
  7. Xia Y, Midoun S, Xu Z, Hong L. Heixuedian (heix), a potential melanotic tumor suppressor gene, exhibits specific spatial and temporal expression pattern during Drosophila hematopoiesis. Dev Biol. 2015;398:218-30 pubmed publisher
    The Drosophila heixuedian (heix) is the ortholog of human UBIAD1 gene (a.k.a TERE1). The protein product of UBIAD1/heix has multiple enzymatic activities, including the vitamin K2 and the non-mitochondrial CoQ10 biosynthesis...