Haspin

Summary

Gene Symbol: Haspin
Description: haspin
Alias: BcDNA:LD07633, CG40080, Dmel\CG40080, haspin, haspin, CG40080-PA, Haspin-PA
Species: fruit fly

Top Publications

  1. Higgins J. Haspin-like proteins: a new family of evolutionarily conserved putative eukaryotic protein kinases. Protein Sci. 2001;10:1677-84 pubmed
    b>Haspin (haploid germ cell-specific nuclear protein kinase) is reported to be a serine/threonine kinase that may play a role in cell-cycle cessation and differentiation of haploid germ cells...
  2. Coulthard A, Alm C, Cealiac I, Sinclair D, Honda B, Rossi F, et al. Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2. Genetics. 2010;185:479-95 pubmed publisher
  3. Xie J, Wooten M, Tran V, Chen B, Pozmanter C, Simbolon C, et al. Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline. Cell. 2015;163:920-33 pubmed publisher
    ..Finally, compromising the activity of the H3T3 kinase Haspin enhances the H3T3A but suppresses the H3T3D phenotypes...
  4. Nakayama M, Suzuki E, Tsunoda S, Hama C. The Matrix Proteins Hasp and Hig Exhibit Segregated Distribution within Synaptic Clefts and Play Distinct Roles in Synaptogenesis. J Neurosci. 2016;36:590-606 pubmed publisher
    ..These results reveal the molecular mechanisms of synaptic matrix construction and illuminate a molecular architecture within synaptic clefts previously unrevealed in any animal species. ..