Genomes and Genes
Gene Symbol: Galphaf
Description: G protein alpha f subunit
Alias: CG12232, Dmel\CG12232, GNAS/L, Galpha73B, Galpha73b, Galpha[[f]]73B, Gfalpha, G protein alpha f subunit, CG12232-PA, G protein alpha 73B, GTP-binding protein alpha-subunit, Galphaf-PA, Gf alpha
Species: fruit fly
- Bausek N, Zeidler M. G?73B is a downstream effector of JAK/STAT signalling and a regulator of Rho1 in Drosophila haematopoiesis. J Cell Sci. 2014;127:101-10 pubmed publisher..As such, we suggest a mechanism by which JAK/STAT pathway signalling may promote metastasis. ..
- Krishnan A, Mustafa A, AlmÃ©n M, Fredriksson R, Williams M, SchiÃ¶th H. Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families. Mol Phylogenet Evol. 2015;91:27-40 pubmed publisher..Our robust classification/hierarchy is essential to further understand the differential roles of GPCR/G protein mediated intracellular signaling system across various metazoan lineages. ..
- Jung A, Hollmann M, Schäfer M. The fatty acid elongase NOA is necessary for viability and has a somatic role in Drosophila sperm development. J Cell Sci. 2007;120:2924-34 pubmed..An RNAi construct selectively driven in cyst cells leads to male sterility, demonstrating the necessity of noa function for male germline development and the interaction of the somatic cyst cells with the developing sperm. ..
- Yao C, Carlson J. Role of G-proteins in odor-sensing and CO2-sensing neurons in Drosophila. J Neurosci. 2010;30:4562-72 pubmed publisher..Ggamma30A is also required for normal CO2 response. The simplest interpretation of these results is that Galpha(q) and Ggamma30A play a role in the response of CO2-sensing neurons, but are not required for Or-mediated odor signaling. ..