Research Topics
Genomes and GenesSpecies | Fbp1SummaryGene Symbol: Fbp1 Description: Fat body protein 1 Alias: CG17285, DmeFBP1, Dmel\CG17285, FBP-1, FBP1, Fbp-1, LP07910p, fbp-1, fbp1, CG17285-PA, CG17285-PB, CG17285-PD, Fbp1-PA, Fbp1-PB, Fbp1-PD, Protein-1, fat body protein 1, fat body protein-1, fat body protein1 Species: fruit fly Top Publications
|
Detail Information
Publications
Ecdysone-inducible functions of larval fat bodies in DrosophilaJ A Lepesant
Proc Natl Acad Sci U S A 75:5570-4. 1978....
The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosisG J Fisk
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, Salt Lake City 84112 5331, USA
Cell 93:543-55. 1998..We propose that DHR78 is a ligand-activated receptor that plays a central role in directing the onset of Drosophila metamorphosis...- Ecdysone-regulation of synthesis and processing of fat body protein 1, the larval serum protein receptor of Drosophila melanogasterT Burmester
Institut Jacques Monod, Biologie du Développement, CNRS et Université Paris 6 et Paris 7, France
Eur J Biochem 262:49-55. 1999..Here, we show that the product of the ecdysteroid-inducible gene Fbp-1 (Fat Body Protein 1) is the receptor that binds LSP-1... - Dual requirement for the EcR/USP nuclear receptor and the dGATAb factor in an ecdysone response in Drosophila melanogasterV Brodu
Institut Jacques Monod, Laboratoire de Biologie du Developpement, CNRS UMR 7592, Universite Paris 7 Denis Diderot, Université Paris 6 P et M Curie, 75251 Paris Cedex 05, France
Mol Cell Biol 19:5732-42. 1999..b>Fbp1 is a good model of primary ecdysone response gene expressed in the fat body for addressing this question... - Genetic and molecular analysis in the 70CD region of the third chromosome of Drosophila melanogasterT Burmester
Department of Genetics, Attila Jozsef University, H 6726, Szeged, Hungary
Gene 246:157-67. 2000..The genomic sequence of the l(3)70Ca/b gene reveals a novel heat shock protein (hsc70Cb). l(3)70Da was identified as a member of the CDC48/PEX1 ATPase family and its coding sequence was determined... - Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of DrosophilaPetros Ligoxygakis
Institut de Biologie Moléculaire and Cellulaire, Strasbourg Cedex, France
EMBO Rep 3:666-73. 2002..18-Wheeler does not qualify as a pattern recognition receptor of Gram-negative bacteria... - Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in DrosophilaMichael Bialecki
Howard Hughes Medical Institute, Department of Human Genetics, 15 North 2030 East, University of Utah, Salt Lake City 84112, USA
Dev Cell 3:209-20. 2002..We propose that ecdysteroid-induced E75A expression defines a feed-forward pathway that amplifies or maintains the ecdysteroid titer during larval development, ensuring proper temporal progression through the life cycle... - Isolation and characterization of hemolymph clotting factors in Drosophila melanogaster by a pullout methodChristoph Scherfer
Department of Molecular Biology and Functional Genomics, University of Stockholm, 10691 Stockholm, Sweden
Curr Biol 14:625-9. 2004..The most abundant clot protein is Hemolectin, and we confirm that hemolectin mutant larvae show clotting defects... - microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in DrosophilaJishy Varghese
European Molecular Biology Laboratory, 69117, Heidelberg, Germany
Genes Dev 21:2277-82. 2007..Failure to limit EcR levels is responsible for the many of the defects observed in miR-14 mutants. miR-14 plays a key role in modulating the positive autoregulatory loop by which Ecdysone sensitizes its own signaling pathway... - Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activityAaron Pinnola
Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
J Biol Chem 282:32511-9. 2007..Therefore, our data collectively suggests a model in which both the regulation of PARP1 protein binding to chromatin and the enzymatic activation of PARP1 protein depend on the dynamics of nucleosomal core histone mediation... - Prothoracicotropic hormone regulates developmental timing and body size in DrosophilaZofeyah McBrayer
The Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
Dev Cell 13:857-71. 2007..These results indicate that final body size in insects is determined by a balance between growth-rate regulators such as insulin and developmental timing cues such as PTTH that set the duration of the feeding interval... 
Functional and bioinformatics analyses reveal conservation of cis-regulatory elements between sciaridae and drosophilidaeMatheus S Lecci
Departamento de Analises Clinicas, Toxicológicas e Bromatológicas DACTB, Faculdade de Ciências Farmacêuticas de Ribeirão Preto FCFRP, Universidade de Sao Paulo USP, Ribeirao Preto, SP, Brazil
Genesis 46:43-51. 2008....- Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosionTatiana Kozlova
Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah 84112 5330, USA
Dev Dyn 238:701-7. 2009..In contrast, cuticle gene expression is significantly reduced in DHR38(Y214) mutant pupae. These studies define the essential functions of DHR38 and provide a genetic context for further characterization of its roles during development... - crooked legs encodes a family of zinc finger proteins required for leg morphogenesis and ecdysone-regulated gene expression during Drosophila metamorphosisP P D'Avino
Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112 5331, USA
Development 125:1733-45. 1998..The genetic criteria described here provide a new direction for identifying regulators of adult tissue development during insect metamorphosis... - Direct repeats bind the EcR/USP receptor and mediate ecdysteroid responses in Drosophila melanogasterC Antoniewski
Institut Jacques Monod, CNRS et Université Paris, France
Mol Cell Biol 16:2977-86. 1996..elements (EcREs) such as those present in the promoter of the hsp27 gene or the fat body-specific enhancer of the Fbp1 gene... - Drosophila Sgs genes: stage and tissue specificity of hormone responsivenessM Lehmann
Institut für Genetik Freie Universität Berlin, Germany
Bioessays 18:47-54. 1996..g. secretion enhancer binding proteins, which act together in a synergistic manner with the 20E receptor and early gene products to establish a stage- and tissue-specific expression pattern... - Hormones, puffs and flies: the molecular control of metamorphosis by ecdysoneA J Andres
Howard Hughes Medical Institute, Eccles Institute of Human Genetics, University of Utah, Salt Lake City 84112
Trends Genet 8:132-8. 1992..Molecular characterization of some of these genes has provided valuable clues to regulatory mechanisms by which the ecdysone signal is transduced and amplified... - Structure of the ecdysone-inducible P1 gene of Drosophila melanogasterF Maschat
Institut Jacques Monod CNRS et Université Paris 7, France
J Mol Biol 214:359-72. 1990..Short stretches of nucleotide sequences similar to sequences located in the 5' regions of other genes expressed in the D. melanogaster fat body were found in the proximal promoter and transcribed region of the P1 gene... - Transformation mapping of the regulatory elements of the ecdysone-inducible P1 gene of Drosophila melanogasterF Maschat
Institut Jacques Monod, Centre National de la Recherche Scientifique, Paris, France
Mol Cell Biol 11:2913-7. 1991..Sequences from -138 to -68 are essential for this expression... - Larval fat body-specific gene expression in D. melanogasterJ Deutsch
Institut Jacques Monod, CNRS Université Paris, France
Dev Genet 10:220-31. 1989..This region includes an element that behaves as a fat-body transcriptional enhancer and element(s) required for ecdysone inducibility of transcription of the P1 gene... - Histochemical analysis of the ecdysterone-regulated expression of the Drosophila genes P1 and LSP-2M L Paco-Larson
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511
Dev Genet 7:197-203. 1986.... - Developmentally regulated gene expression in Drosophila larval fat bodiesJ A Lepesant
J Mol Appl Genet 1:371-83. 1982..Ecdysterone increases the level of the P1 transcript, but not of the P6 transcript, in ecdysterone-deficient ecd1 larvae... - Insect nuclear receptors: a developmental and comparative perspectiveV C Henrich
Department of Biology, University of North Carolina Greensboro 27412 5001, USA
Insect Biochem Mol Biol 25:881-97. 1995..As receptor homologues have been identified in other insects, several general ideas concerning insect hormonal regulation have begun to emerge and these will be examined from a comparative point of view... - The ecdysone response enhancer of the Fbp1 gene of Drosophila melanogaster is a direct target for the EcR/USP nuclear receptorC Antoniewski
Institut Jacques Monod, Centre National de la Recherche Scientifique, Paris, France
Mol Cell Biol 14:4465-74. 1994The transcription of the Drosophila melanogaster Fbp1 gene is induced by the steroid hormone 20-hydroxyecdysone and restricted to the late-third-instar fat body tissue... - In vivo functional characterization of an ecdysone response enhancer in the proximal upstream region of the Fbp1 gene of D. melanogasterM Laval
Institut Jacques Monod, CNRS et Université Paris, France
Mech Dev 44:123-38. 1993Transcription of the D. melanogaster Fat-body-protein-1 (Fbp1) gene is induced by the steroid hormone 20-hydroxyecdysone and is restricted to the fat body tissue at the end of the third larval instar... - Deletion scanning of the regulatory sequences of the Fbp1 gene of Drosophila melanogaster using P transposase-induced deficienciesP Lapie
Laboratoire de Biologie du Developpement, Institut Jacques Monod, CNRS, Paris, France
Genetics 135:801-16. 1993..remains fixed was applied to the study of the upstream sequences of the ecdysteroid-inducible Fat-body-protein-1 (Fbp1) gene. Deficiencies were induced in a Fbp1:Adh fusion transgene by means of a secondary P transposase mutagenesis... - Structural features critical to the activity of an ecdysone receptor binding siteC Antoniewski
Institut Jacques Monod, CNRS, Paris, France
Insect Biochem Mol Biol 23:105-14. 1993Two ecdysone-response elements from the hsp27 (hsp27 EcRE) and the Fbp1 (D EcRE) genes of Drosophila melanogaster were used as probes in a gel shift assay to investigate the interactions of the ecdysone receptor (EcR) with its cognate DNA .. - Characterization of an EcR/USP heterodimer target site that mediates ecdysone responsiveness of the Drosophila Lsp-2 geneC Antoniewski
Institut Jacques Monod, Centre National de la Recherche Scientifique and Université de Paris 7, France
Mol Gen Genet 249:545-56. 1995..complex is comparable to that of the canonical EcRE of the hsp27 gene and is at least 4-fold greater than that of Fbp1, another fat body-specific Drosophila gene... - Hormonal regulation of the E75 gene in Drosophila: identifying functional regulatory elements through computational and biological analysisTravis J Bernardo
Department of Biology, Fordham University, Bronx, NY 10458, USA
J Mol Biol 387:794-808. 2009..We propose that the presence of multiple EcREs with distinct features provides flexibility to the rapid and powerful response of E75A to ecdysone during Drosophila development...