Gene Symbol: eIF-5A
Description: eIF-5A
Alias: 1296, CG3186, Dmel\CG3186, anon-EST:fe2H10, chr2R:19566878..19566998, eIF5A, eIF5a, l(2)01296, eIF-5A, CG3186-PA, CG3186-PB, anon-fast-evolving-2H10, eIF-5A-PA, eIF-5A-PB, eukaryotic initiation factor 5A, eukaryotic translation factor 5A
Species: fruit fly

Top Publications

  1. Galloni M, Edgar B. Cell-autonomous and non-autonomous growth-defective mutants of Drosophila melanogaster. Development. 1999;126:2365-75 pubmed
    ..The isolation of non-cell-autonomous larval growth-defective mutants suggests that specialized organs coordinate growth throughout the animal and provides new tools for studies of organismal growth regulation. ..
  2. Swanson W, Clark A, Waldrip Dail H, Wolfner M, Aquadro C. Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila. Proc Natl Acad Sci U S A. 2001;98:7375-9 pubmed
    ..The evolutionary EST approach applied here to identify putative targets of adaptive evolution is readily applicable to other tissues and organisms. ..
  3. Patel P, Costa Mattioli M, Schulze K, Bellen H. The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. J Cell Biol. 2009;185:1181-94 pubmed publisher
    ..eIF5A (eukaryotic initiation factor 5A) is the only known protein to contain hypusine...
  4. Parry T, Theisen J, Hsu J, Wang Y, Corcoran D, Eustice M, et al. The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. Genes Dev. 2010;24:2013-8 pubmed publisher
    ..Thus, the TCT motif is a novel transcriptional element that is distinct from the Inr. These findings reveal a specialized TCT-based transcription system that is directed toward the synthesis of ribosomal proteins. ..
  5. Creagh E, Brumatti G, Sheridan C, Duriez P, Taylor R, Cullen S, et al. Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival. PLoS ONE. 2009;4:e5055 pubmed publisher
    ..These data suggest that bicaudal/betaNAC is essential for cell survival and is a conserved target of caspases from flies to man. ..
  6. Herrig D, Modrick A, Brud E, Llopart A. Introgression in the Drosophila subobscura--D. Madeirensis sister species: evidence of gene flow in nuclear genes despite mitochondrial differentiation. Evolution. 2014;68:705-19 pubmed publisher
    ..Contrary to other observations in Drosophila, the mitochondrial genome appears resilient to gene flow in the presence of nuclear exchange...