Gene Symbol: e(y)1
Description: enhancer of yellow 1
Alias: CG6474, Dmel\CG6474, TAF40, TAF40/42, TAF40/42/e(y)1, TAF42, TAF9, TAFII40, TAFII40(42), TAF[II]40, TAF[[II]], TAF[[II]]40, TAF[[II]]40/42, TAF[[II]]42, TFIID, TFIID 42, TFIID-p42, Taf40, Taf42, Taf9, TafII40, Taf[[II]]40, d40, dTAF42, dTAF9, dTAFII42, dTAF[[40]], dTAF[[II]]40, dTAF[[II]]42, dmTAF9, dmTaf9, dme-TAFII40, p42, taf40/e(y)1, enhancer of yellow 1, CG6474-PA, TBP-associated factor, TBP-associated factor 40kD, e(y)1-PA, enhancer of yellow 4
Species: fruit fly
Products:     e(y)1

Top Publications

  1. Lively T, Ferguson H, Galasinski S, Seto A, Goodrich J. c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro. J Biol Chem. 2001;276:25582-8 pubmed
    ..by c-Jun depends on the TATA-binding protein (TBP)-associated factor (TAF) subunits of transcription factor IID (TFIID)...
  2. Chen Z, Manley J. In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. J Biol Chem. 2003;278:35172-83 pubmed
    The majority of the TATA-binding protein (TBP)-associated factors (TAFs) that constitute transcription factor II D (TFIID) contain histone fold motifs (HFMs)...
  3. Gause M, Georgieva S, Georgiev P. Phenotypic reversion of the gypsy-induced mutation scD1 of Drosophila melanogaster by replicative transposition of a sc enhancer to the yellow gene and by mutations in the enhancer of yellow and zeste loci. Mol Gen Genet. 1996;253:370-6 pubmed
    ..In addition, we found that mutations in the e(y)1, e(y)3 and zeste genes may interfere with transcriptional insulation by the su(Hw)-binding region in the scD1 allele. ..
  4. Zhou J, Zwicker J, Szymanski P, Levine M, Tjian R. TAFII mutations disrupt Dorsal activation in the Drosophila embryo. Proc Natl Acad Sci U S A. 1998;95:13483-8 pubmed
    In this study, we present evidence that the Dorsal activator interacts with limiting amounts of the TFIID complex in the Drosophila embryo...
  5. Tora L. A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. Genes Dev. 2002;16:673-5 pubmed
  6. Georgieva S, Gauze M. [Protein products of zeste, e(y)1 and e(y)3 genes can effect the insulation process]. Dokl Akad Nauk. 1998;358:260-2 pubmed
  7. Melnikova L, Kostyuchenko M, Georgiev P. The promoter activation at the end of terminally truncated chromosome in Drosophila melanogaster. Dokl Biochem Biophys. 2014;459:204-8 pubmed publisher
  8. Metcalf C, Wassarman D. Nucleolar colocalization of TAF1 and testis-specific TAFs during Drosophila spermatogenesis. Dev Dyn. 2007;236:2836-43 pubmed
    ..tTAFs are paralogs of generally expressed TAF subunits of transcription factor IID (TFIID)...
  9. Leibovitch B, Lu Q, Benjamin L, Liu Y, Gilmour D, Elgin S. GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter. Mol Cell Biol. 2002;22:6148-57 pubmed
    ..we have created flies with an hsp26/lacZ transgene wherein the entire DNA segment known to interact with the TFIID complex has been replaced by a random sequence...

More Information


  1. Petty K, Krimkevich Y, Thomas D. A TATA binding protein-associated factor functions as a coactivator for thyroid hormone receptors. Mol Endocrinol. 1996;10:1632-45 pubmed
    ..Thus, TAFII110 functions as a cofactor for TRs, and the interactions between specific TAFs and nuclear receptors may provide another level of selectivity for transcriptional responses to hormones. ..
  2. Soldatov A, Nabirochkina E. [A new method of cloning Drosophila melanogaster genes marked with a highly copies mobile genetic element]. Genetika. 1996;32:1717-20 pubmed
    ..melanogaster strains differing only in genomic location of the studied gene to be obtained. This method allowed the e(y)1 gene marked with an insert of the Stalker highly copied transposon to be cloned [1]. ..
  3. Damania B, Alwine J. TAF-like function of SV40 large T antigen. Genes Dev. 1996;10:1369-81 pubmed
    ..to epitope-tagged TBP, endogenous TBP, hTAF(II)100, hTAF(II)130, and hTAF(II)250, under conditions where holo-TFIID would be precipitated...
  4. Wang Y, Brock H. Polyhomeotic stably associates with molecular chaperones Hsc4 and Droj2 in Drosophila Kc1 cells. Dev Biol. 2003;262:350-60 pubmed
    ..We discuss the role of chaperones and F-PHP-HA-associated proteins in PcG-mediated silencing and the evidence for different complexes containing Polyhomeotic in vivo. ..
  5. Pugh B. Control of gene expression through regulation of the TATA-binding protein. Gene. 2000;255:1-14 pubmed
    ..The magnitude by which an activated gene is expressed, and thus repeatedly transcribed, might depend in part on competition between TBP inhibitors and the holoenzyme for access to the TBP/TATA complex. ..
  6. Burley S. X-ray crystallographic studies of eukaryotic transcription factors. Cold Spring Harb Symp Quant Biol. 1998;63:33-40 pubmed
  7. Santoso B, Kadonaga J. Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300. Nat Struct Mol Biol. 2006;13:131-9 pubmed
    ..Hence, the mechanism of transcriptional repression by p300 is distinct from that of histone H1, PARP-1 or Sir2. These findings reveal a novel chromatin-specific repressive function of p300. ..
  8. Nogales E. Recent structural insights into transcription preinitiation complexes. J Cell Sci. 2000;113 Pt 24:4391-7 pubmed
    ..of X-ray crystallography and NMR studies, more global pictures of multisubunit transcription complexes, such as TFIID, TFIIH or the yeast mediator, have now been obtained by electron microscopy and image-reconstruction techniques...
  9. Kokubo T, Takada R, Yamashita S, Gong D, Roeder R, Horikoshi M, et al. Identification of TFIID components required for transcriptional activation by upstream stimulatory factor. J Biol Chem. 1993;268:17554-8 pubmed
    A TATA box-binding initiation factor, TFIID, plays a central role in the transcriptional regulation by activators...
  10. Georgiev P, Kiselev S, Simonova O, Gerasimova T. A novel transposition system in Drosophila melanogaster depending on the Stalker mobile genetic element. EMBO J. 1990;9:2037-44 pubmed
    ..Many known and novel mutations have been obtained. Comparison of their genetic localization with Stalker distribution suggests that the majority of them have been induced by the Stalker insertion. ..
  11. Rodriguez Navarro S. Insights into SAGA function during gene expression. EMBO Rep. 2009;10:843-50 pubmed publisher
    ..I focus particularly on the new components of human SAGA, which was recently discovered and confirms the conservation of the SAGA complex throughout evolution. ..
  12. Lebedeva L, Nabirochkina E, Kurshakova M, Robert F, Krasnov A, Evgen ev M, et al. Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation. Proc Natl Acad Sci U S A. 2005;102:18087-92 pubmed
  13. Kind J, Vaquerizas J, Gebhardt P, Gentzel M, Luscombe N, Bertone P, et al. Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila. Cell. 2008;133:813-28 pubmed publisher
    ..Therefore, MOF is not only involved in the onset of dosage compensation, but also acts as a regulator of gene expression in the Drosophila genome. ..
  14. Bezborodova E, Kulikov A, Georgiev P. A new family of genes which, when mutated, suppress the inhibitory effect of the mod(mdg4)1u1 mutation on y2 expression in Drosophila melanogaster. Mol Gen Genet. 1997;257:83-90 pubmed
    ..Most of Su(mg) mutations do not affect the viability or fertility of homozygous flies. We speculate that the Su(mg) genes represent a new family of redundant regulatory genes in Drosophila melanogaster. ..
  15. Georgiev P, Gerasimova T. Novel genes influencing the expression of the yellow locus and mdg4 (gypsy) in Drosophila melanogaster. Mol Gen Genet. 1989;220:121-6 pubmed
    ..All e(y)n genes are located in different regions of the X chromosome. One may speculate that e(y)n genes are involved in trans-regulation of the yellow locus and possibly of some other loci. ..
  16. Farmer G, Colgan J, Nakatani Y, Manley J, Prives C. Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo. Mol Cell Biol. 1996;16:4295-304 pubmed
    ..Overexpression of TAFII40 and TAFII60 also inhibited activation by p53-GAL4 but had negligible effects on activation by GAL4-VP16 and Sp1, ..
  17. Dynlacht B, Hoey T, Tjian R. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation. Cell. 1991;66:563-76 pubmed
    ..fractionated Drosophila basal factors reveals that activation by NTF-1 requires factors present in the endogenous TFIID fraction that are distinct from the purified TATA-binding protein (TBP)...
  18. Fan W, Lam S, Xin J, Yang X, Liu Z, Liu Y, et al. Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. PLoS Genet. 2017;13:e1006664 pubmed publisher
    The general transcription factor TBP (TATA-box binding protein) and its associated factors (TAFs) together form the TFIID complex, which directs transcription initiation...
  19. Mahanta S, Scholl T, Yang F, Strominger J. Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation of multiple regions of the TATA box binding protein. Proc Natl Acad Sci U S A. 1997;94:6324-9 pubmed
    ..Overall the mechanism of transactivation by the human B-cell-specific CIITA is very similar to that mediated by the herpes virus transactivator VP16 in the ways that have been tested. ..
  20. Vorobyeva N, Soshnikova N, Kuzmina J, Kopantseva M, Nikolenko J, Nabirochkina E, et al. The novel regulator of metazoan development SAYP organizes a nuclear coactivator supercomplex. Cell Cycle. 2009;8:2152-6 pubmed
    ..is related to the conserved domain SAY, which assembles a nuclear supercomplex BTFly consisting of Brahma and TFIID coactivators...
  21. Kennett S, Moorefield K, Horowitz J. Sp3 represses gene expression via the titration of promoter-specific transcription factors. J Biol Chem. 2002;277:9780-9 pubmed
    ..We conclude that Sp3- mediated transcriptional repression is due, at least in part, to competition for promoter-specific transcription factors. ..
  22. Wright K, Marr M, Tjian R. TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter. Proc Natl Acad Sci U S A. 2006;103:12347-52 pubmed
    Activator-dependent recruitment of TFIID initiates formation of the transcriptional preinitiation complex...
  23. Kozitsina M, Abramova N, Georgiev P. [Interaction between the enhancers of yellow and the yellow gene in Drosophila melanogaster]. Genetika. 1992;28:59-67 pubmed
    ..At the same time, the interaction of here described gene e(y)7 with the yellow gene is likely to occur at the level of protein products. ..
  24. Elagin V, Medvedeva N, Georgiev P. [Mutations affecting intrachromosomal recombination and conversion in the binary y(2ns)sc(me) system in Drosophila melanogaster]. Genetika. 1994;30:330-6 pubmed
    ..Some of the mutations under study also modify the phenotypic manifestation of the y2nsscme allele. ..
  25. Mohan R, Dialynas G, Weake V, Liu J, Martin Brown S, Florens L, et al. Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration. Genes Dev. 2014;28:259-72 pubmed publisher
    ..When we examined the consequences of reduced Ataxin-7 in vivo, we found that flies exhibited pronounced neural and retinal degeneration, impaired movement, and early lethality...
  26. Vorobyeva N, Soshnikova N, Nikolenko Y, Nabirochkina E, Georgieva S, Shidlovskii Y. A new evolutionarily conserved protein domain is capable of transcription activation. Dokl Biochem Biophys. 2008;423:349-51 pubmed
  27. Mantovani R. The molecular biology of the CCAAT-binding factor NF-Y. Gene. 1999;239:15-27 pubmed
    ..This review focuses on the CCAAT sequence and on the NF-Y protein, also known as CBF, which binds to it. ..
  28. Verrijzer C, Chen J, Yokomori K, Tjian R. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell. 1995;81:1115-25 pubmed
    ..Here, we have assessed the potential role of TAFs and the TFIID complex in directing basal promoter function...
  29. Hoey T, Weinzierl R, Gill G, Chen J, Dynlacht B, Tjian R. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell. 1993;72:247-60 pubmed
    The general transcription factor TFIID is a multiprotein complex containing the TATA-binding protein and several associated factors (TAFs), some of which may function as coactivators that are essential for activated, but not basal, ..
  30. Nakatani Y, Bagby S, Ikura M. The histone folds in transcription factor TFIID. J Biol Chem. 1996;271:6575-8 pubmed
    ..We have previously reported that the N-terminal regions of dTAFII62 and dTAFII42 have sequence similarities with histones H4 and H3...
  31. Georgieva S, Kirschner D, Jagla T, Nabirochkina E, Hanke S, Schenkel H, et al. Two novel Drosophila TAF(II)s have homology with human TAF(II)30 and are differentially regulated during development. Mol Cell Biol. 2000;20:1639-48 pubmed
    b>TFIID is a multiprotein complex composed of the TATA binding protein (TBP) and TBP-associated factors (TAF(II)s)...
  32. Soldatov A, Nabirochkina E, Georgieva S, Belenkaja T, Georgiev P. TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations. Mol Cell Biol. 1999;19:3769-78 pubmed
    The enhancer of yellow 1 gene, e(y)1, of Drosophila melanogaster has been cloned and demonstrated to encode the TAFII40 protein...
  33. Weinzierl R, Ruppert S, Dynlacht B, Tanese N, Tjian R. Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID. EMBO J. 1993;12:5303-9 pubmed
    Regulation of transcription initiation by RNA polymerase II requires TFIID, a multisubunit complex composed of the TATA binding protein (TBP) and at least seven tightly associated factors (TAFs)...
  34. Gangloff Y, Pointud J, Thuault S, Carre L, Romier C, Muratoglu S, et al. The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger. Mol Cell Biol. 2001;21:5109-21 pubmed
    The RNA polymerase II transcription factor TFIID comprises the TATA binding protein (TBP) and a set of TBP-associated factors (TAF(II)s)...
  35. Hoffmann A, Chiang C, Oelgeschlager T, Xie X, Burley S, Nakatani Y, et al. A histone octamer-like structure within TFIID. Nature. 1996;380:356-9 pubmed
    The general transcription factor TFIID nucleates initiation complex formation through direct core promoter binding, commits promoters within chromatin to transcription, and mediates the action of transcriptional activators, a phenomenon ..
  36. Kusch T, Guelman S, Abmayr S, Workman J. Two Drosophila Ada2 homologues function in different multiprotein complexes. Mol Cell Biol. 2003;23:3305-19 pubmed
    ..This suggests that the mammalian and fly homologues of the transcriptional adapter Ada2 form two functionally distinct subgroups with unique characteristics. ..
  37. Chen J, Tjian R. Reconstitution of TATA-binding protein-associated factor/TATA-binding protein complexes for in vitro transcription. Methods Enzymol. 1996;273:208-17 pubmed
  38. Purnell B, Emanuel P, Gilmour D. TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes. Genes Dev. 1994;8:830-42 pubmed
    Immunopurified TFIID produces a large DNase I footprint over the hsp70, hsp26, and histone H3 promoters of Drosophila...
  39. Soldatov A, Nabirochkina E, Dzitoeva S, Matiunina L, Georgiev P. [Molecular cloning of regions of localization of the e(y)1 and e(y)2 genes in Drosophila melanogaster]. Genetika. 1996;32:1714-6 pubmed
    ..Molecular cloning of the e(y)1 and e(y)2 gene regions is described. The results of cloning were confirmed by experiments on the rescue of the mutant phenotype. ..
  40. Dynlacht B, Weinzierl R, Admon A, Tjian R. The dTAFII80 subunit of Drosophila TFIID contains beta-transducin repeats. Nature. 1993;363:176-9 pubmed
    A key component of the RNA polymerase II transcriptional apparatus, TFIID, is a multi-protein complex containing the TATA box-binding protein (TBP) and at least seven tightly associated factors (TAFs)...
  41. Xie X, Kokubo T, Cohen S, Mirza U, Hoffmann A, Chait B, et al. Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature. 1996;380:316-22 pubmed
    ..0A resolution. The amino-terminal portions of dTAFII42 and dTAFII62 from Drosophila adopt the canonical histone fold, consisting of two short alpha-helices flanking a ..
  42. Berk A. Activation of RNA polymerase II transcription. Curr Opin Cell Biol. 1999;11:330-5 pubmed
    ..TATA-box binding protein associated factor (TAF) subunits of yeast TFIID were found to be generally required for transcription in vivo...
  43. Kokubo T, Gong D, Wootton J, Horikoshi M, Roeder R, Nakatani Y. Molecular cloning of Drosophila TFIID subunits. Nature. 1994;367:484-7 pubmed
    Transcription initiation factor TFIID is a multisubunit complex containing a TATA-box-binding factor (TFIID tau/TBP) and associated polypeptide factors (TAFs) with sizes ranging from M(r) approximately 20,000 to > 200,000...
  44. Xie G, Yu Z, Jia D, Jiao R, Deng W. E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila. J Cell Sci. 2014;127:3830-9 pubmed publisher
    ..Here, we report that E(y)1/TAF9, a component of the transcription factor TFIID complex, interacts specifically with the NICD-Su(H)-Mam complex to facilitate the transcriptional output of Notch ..
  45. Burke T, Kadonaga J. The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. Genes Dev. 1997;11:3020-31 pubmed
    ..a seven- to eightfold reduction in transcription as well as a significant reduction in the binding of purified TFIID. These results suggest a specific and somewhat rigid interaction of TFIID with the Inr and DPE sequences...
  46. Guelman S, Suganuma T, Florens L, Weake V, Swanson S, Washburn M, et al. The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Mol Cell Biol. 2006;26:7178-89 pubmed
    ..Our results point to a critical function of dSAGA and histone acetylation during Drosophila development. ..
  47. Georgiev P. Identification of mutations in three genes that interact with zeste in the control of white gene expression in Drosophila melanogaster. Genetics. 1994;138:733-9 pubmed
    ..The products of these three genes may represent, together with zeste, a group of proteins involved in the organization of long-distance interactions between DNA sequences...
  48. Goodrich J, Hoey T, Thut C, Admon A, Tjian R. Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell. 1993;75:519-30 pubmed
    ..Here we report the molecular cloning, expression, and biochemical characterization of Drosophila TAFII40 (dTAFII40), a subunit of TFIID...
  49. Yokomori K, Admon A, Goodrich J, Chen J, Tjian R. Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex. Genes Dev. 1993;7:2235-45 pubmed
    ..While characterizing the Drosophila TFIID complex, we discovered that a 30-kD protein that cofractionated with dTFIID was homologous to the previously ..
  50. Belen kaia T, Georgiev P. [Role of the "enhancer of yellow" genes in the regulation of expression of the "yellow" gene in Drosophila melanogaster]. Genetika. 1999;35:432-7 pubmed
    The e(y)1/TAFII40, e(y)2 and e(y)3 genes encode general transcription factors in Drosophila melanogaster...
  51. Chen J, Attardi L, Verrijzer C, Yokomori K, Tjian R. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell. 1994;79:93-105 pubmed
    We previously reported that transcriptional regulators can bind selected TAF subunits of the TFIID complex. However, the specificity and function of individual TAFs in mediating transcriptional activation remained unknown...
  52. Albright S, Tjian R. TAFs revisited: more data reveal new twists and confirm old ideas. Gene. 2000;242:1-13 pubmed
    ..Coordinating the interaction of these proteins is the basal transcription factor TFIID, which recognizes the core promoter and supplies a scaffolding upon which the rest of the transcriptional ..
  53. Verrijzer C, Yokomori K, Chen J, Tjian R. Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science. 1994;264:933-41 pubmed
    In Drosophila and human cells, the TATA binding protein (TBP) of the transcription factor IID (TFIID) complex is tightly associated with multiple subunits termed TBP-associated factors (TAFs) that are essential for mediating regulation ..
  54. Wright K, Tjian R. Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivo. Proc Natl Acad Sci U S A. 2009;106:55-60 pubmed publisher
    Understanding the diverse activities of the multisubunit core promoter recognition complex TFIID in vivo requires knowledge of how individual subunits contribute to overall functions of this TATA box-binding protein (TBP)/TBP-associated ..
  55. Sandaltzopoulos R, Becker P. Heat shock factor increases the reinitiation rate from potentiated chromatin templates. Mol Cell Biol. 1998;18:361-7 pubmed
    ..Well-documented transcription activation mechanisms, such as the recruitment of TFIID and TFIIB, control the early phases of preinitiation complex formation...
  56. Georgieva S, Nabirochkina E, Dilworth F, Eickhoff H, Becker P, Tora L, et al. The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates. Mol Cell Biol. 2001;21:5223-31 pubmed
    ..studies demonstrate that the major complex, including both proteins, appears to be distinct from TFIID. Furthermore, we provide genetic evidence suggesting that the carboxy terminus of dTAF(II)40 is important for ..
  57. Duttke S. Evolution and diversification of the basal transcription machinery. Trends Biochem Sci. 2015;40:127-9 pubmed publisher
  58. Burke T, Willy P, Kutach A, Butler J, Kadonaga J. The DPE, a conserved downstream core promoter element that is functionally analogous to the TATA box. Cold Spring Harb Symp Quant Biol. 1998;63:75-82 pubmed
  59. Hansen S, Tjian R. TAFs and TFIIA mediate differential utilization of the tandem Adh promoters. Cell. 1995;82:565-75 pubmed
    ..We propose a mechanism for regulating differential promoter utilization during Drosophila development that involves the recognition of specific initiator elements by TAFs in the TFIID complex.
  60. Muratoglu S, Georgieva S, Papai G, Scheer E, Enunlu I, Komonyi O, et al. Two different Drosophila ADA2 homologues are present in distinct GCN5 histone acetyltransferase-containing complexes. Mol Cell Biol. 2003;23:306-21 pubmed
    ..Furthermore, in vivo the two dADA2 proteins showed different localizations on polytene X chromosomes. These results, taken together, suggest that the two Drosophila ADA2 homologues are present in distinct GCN5-containing HAT complexes. ..
  61. Hori R, Pyo S, Carey M. Protease footprinting reveals a surface on transcription factor TFIIB that serves as an interface for activators and coactivators. Proc Natl Acad Sci U S A. 1995;92:6047-51 pubmed
    ..for this interaction to culminate in productive transcription complex assembly, and one such TAF, Drosophila TAF40, reportedly forms a ternary complex with VP16 and TFIIB...
  62. Baxevanis A, Arents G, Moudrianakis E, Landsman D. A variety of DNA-binding and multimeric proteins contain the histone fold motif. Nucleic Acids Res. 1995;23:2685-91 pubmed
    ..It is proposed that these proteins may share a similar three-dimensional conformation despite the lack of significant sequence similarity. ..
  63. Georgieva S, Nabirochkina E, Ladygina N, Georgiev P, Soldatov A. [Nuclear protein e(y)2 from Drosophila melanogaster participates in transcription control]. Genetika. 2001;37:24-8 pubmed
    ..Genetic analysis showed that the C-terminal amino acid residues of transcription factor TAFII40 are important for its interaction with e(y)2.
  64. Lebedeva L, Georgieva S, Nabirochkina E. Study of the properties of two homologues of yeast ADA2 in Drosophila melanogaster. Dokl Biochem Biophys. 2004;398:297-9 pubmed