Gene Symbol: Cyp6t3
Description: Cyp6t3
Alias: 6t3, CG8457, Cyp6T3, Dmel\CG8457, Cyp6t3, CG8457-PA, Cyp6t3-PA
Species: fruit fly

Top Publications

  1. Brandt A, Scharf M, Pedra J, Holmes G, Dean A, Kreitman M, et al. Differential expression and induction of two Drosophila cytochrome P450 genes near the Rst(2)DDT locus. Insect Mol Biol. 2002;11:337-41 pubmed
    ..3-fold; CYP12D1 = 6.0-fold), and (iv) exposure to DDT results in an increased expression of only one of these two P450 genes (CYP12D1 > or = 6-fold above constitutive resistant fly baselines). ..
  2. Daborn P, Boundy S, Yen J, Pittendrigh B, ffrench Constant R. DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid. Mol Genet Genomics. 2001;266:556-63 pubmed
    ..We are now testing the hypothesis that resistance to both compounds is associated with over-expression of this P450 gene. ..
  3. Daborn P, Lumb C, Boey A, Wong W, Ffrench Constant R, Batterham P. Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Insect Biochem Mol Biol. 2007;37:512-9 pubmed
    ..Drosophila over-expressing Cyp6g1, Cyp6g2, Cyp6t3, Cyp6a2, Cyp6a8, Cyp6a19, Cyp6a23 and Cyp12d1 were screened for resistance to four insecticides--DDT, nitenpyram, ..
  4. Bachtrog D, Andolfatto P. Selection, recombination and demographic history in Drosophila miranda. Genetics. 2006;174:2045-59 pubmed
    ..These departures from neutral equilibrium expectations are discussed in the context of nonequilibrium models of demography and selection. ..

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