Gene Symbol: Cyp303a1
Alias: 303a1, BG:DS02740.6, CG4163, CYP303A1-Dm, Cyp303A1, Dmel\CG4163, I(2)35Fb, l(2)35Fb, nompH, Cyp303a1, CG4163-PA, CG4163-PB, Cyp303a1-PA, Cyp303a1-PB, lethal(2)35Fb
Species: fruit fly
Reese M, Hartzell G, Harris N, Ohler U, Abril J, Lewis S. Genome annotation assessment in Drosophila melanogaster. Genome Res. 2000;10:483-501 pubmed
Willingham A, Keil T. A tissue specific cytochrome P450 required for the structure and function of Drosophila sensory organs. Mech Dev. 2004;121:1289-97 pubmed
..organs, we examined mutants with impaired mechanosensation and discovered one, nompH, encodes the cytochrome P450 CYP303a1. We now report the characterization of nompH, a mutant defective in the function of peripheral chemo- and ..
Dawson I, Roth S, Artavanis Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol. 1995;129:725-37 pubmed
..Our data suggest that fzy function is required for normal cell cycle-regulated proteolysis that is necessary for successful progress through mitosis. ..
Niwa R, Matsuda T, Yoshiyama T, Namiki T, Mita K, Fujimoto Y, et al
. CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila. J Biol Chem. 2004;279:35942-9 pubmed
..These results strongly suggest that CYP306A1 functions as a carbon 25 hydroxylase and has an essential role in ecdysteroid biosynthesis during insect development...
Wang S, Hu X, Meng Q, Muhammad S, Chen R, Li F, et al
. The involvement of several enzymes in methanol detoxification in Drosophila melanogaster adults. Comp Biochem Physiol B Biochem Mol Biol. 2013;166:7-14 pubmed publisher
..It seems that there are some differences in methanol metabolism between larvae and adults, but not between female and male adults. ..
Eberl D, Ren D, Feng G, Lorenz L, Van Vactor D, Hall L. Genetic and developmental characterization of Dmca1D, a calcium channel alpha1 subunit gene in Drosophila melanogaster. Genetics. 1998;148:1159-69 pubmed
..Those that do eclose have difficulty in fluid-filling of the wings. These studies show that this member of the calcium channel alpha1 subunit gene family plays a nonredundant, vital role in larvae and adults. ..
Wang S, He G, Chen R, Li F, Li G. The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae. Arch Insect Biochem Physiol. 2012;79:264-75 pubmed publisher
..Their resulting proteins were suggested as the candidate enzymes for methanol metabolism in D. melanogaster larvae. ..