Clp

Summary

Gene Symbol: Clp
Description: Clipper
Alias: CG3642, CLP, CPSF30, Cpsf30, Dmel\CG3642, Ssb-c6a, c6a, clp, clipper, CG3642-PA, Clp-PA, single stranded-binding protein c6a
Species: fruit fly

Top Publications

  1. Stroumbakis N, Li Z, Tolias P. RNA- and single-stranded DNA-binding (SSB) proteins expressed during Drosophila melanogaster oogenesis: a homolog of bacterial and eukaryotic mitochondrial SSBs. Gene. 1994;143:171-7 pubmed
    ..It is expressed as a single 600-nucleotide (nt) transcript during oogenesis and embryogenesis. A larger transcript of 1500 nt is prevalent in some later stages of Dm development. ..
  2. Bai C, Tolias P. Cleavage of RNA hairpins mediated by a developmentally regulated CCCH zinc finger protein. Mol Cell Biol. 1996;16:6661-7 pubmed
    ..identify a developmentally regulated gene from Drosophila melanogaster that encodes a RNase that we refer to as Clipper (CLP)...
  3. Bai C, Tolias P. Drosophila clipper/CPSF 30K is a post-transcriptionally regulated nuclear protein that binds RNA containing GC clusters. Nucleic Acids Res. 1998;26:1597-604 pubmed
    ..The Drosophila melanogaster gene, clipper ( clp ), encodes a homolog of the CPSF 30K subunit...
  4. Sullivan K, Steiniger M, Marzluff W. A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Mol Cell. 2009;34:322-32 pubmed publisher
    ..These results suggest that a common core cleavage factor is required for processing of histone and polyadenylated pre-mRNAs. ..
  5. Tiwari P, Kumar A, Das R, Malhotra V, Vijayraghavan K. A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction. PLoS ONE. 2015;10:e0140976 pubmed publisher
    ..Tango1 knockdown was found to affect development of muscle attachment sites and formation of myotendinous junction. Tango1 was also found to be involved in secretion of Viking (Collagen type IV) and BM-40 from hemocytes and fat cells. ..