Gene Symbol: cib
Description: ciboulot
Alias: CG4944, Dmel\CG4944, EG0007-11, EG:EG0007.11, ciboulot, CG4944-PA, CG4944-PB, CG4944-PC, CG4944-PD, CG4944-PE, beta-thymosin, cib-PA, cib-PB, cib-PC, cib-PD, cib-PE, ciboulet, ciboulout
Species: fruit fly

Top Publications

  1. Thran J, Poeck B, Strauss R. Serum response factor-mediated gene regulation in a Drosophila visual working memory. Curr Biol. 2013;23:1756-63 pubmed publisher
    ..This study provides the first evidence that SRF-mediated gene regulation is also required for a working memory that lasts only for a few seconds. ..
  2. Jodoin J, Coravos J, Chanet S, Vasquez C, Tworoger M, Kingston E, et al. Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover. Dev Cell. 2015;35:685-97 pubmed publisher
    ..Our work identifies a critical role for F-actin turnover in connecting actomyosin to intercellular junctions, defining a dynamic process required for the stability of force balance across intercellular contacts in tissues. ..
  3. Boquet I, Boujemaa R, Carlier M, Preat T. Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell. 2000;102:797-808 pubmed
    ..Here we characterize a novel actin binding protein, Ciboulot (Cib), which plays a major role in axonal growth during Drosophila brain metamorphosis...
  4. Pillmann H, Hatje K, Odronitz F, Hammesfahr B, Kollmar M. Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence homology. BMC Bioinformatics. 2011;12:270 pubmed publisher
    ..Thus, WebScipio should be able to identify mutually exclusive spliced exons in any query sequence from any species with a very high probability. WebScipio is freely available to academics at ..
  5. Doiguchi M, Nakagawa T, Imamura Y, Yoneda M, Higashi M, Kubota K, et al. SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation. Sci Rep. 2016;6:20179 pubmed publisher
    ..The interplay between the remodeling activity of SMARCAD1 and histone acetylation by CBP sheds light on the function of chromatin and the genome-integrity network. ..
  6. Boquet I, Hitier R, Dumas M, Chaminade M, Preat T. Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction. J Neurobiol. 2000;42:33-48 pubmed
    ..This work opens the way for further analysis of the molecular and cellular events involved in central brain reorganization during metamorphosis. ..
  7. Manuel M, Kruse M, Muller W, Le Parco Y. The comparison of beta-thymosin homologues among metazoa supports an arthropod-nematode clade. J Mol Evol. 2000;51:378-81 pubmed
    ..We argue that such discrete molecular character is phylogenetically very powerful and provides strong evidence for the monophyly of an arthropod-nematode clade. ..
  8. Clyne P, Brotman J, Sweeney S, Davis G. Green fluorescent protein tagging Drosophila proteins at their native genomic loci with small P elements. Genetics. 2003;165:1433-41 pubmed
    ..This technology allows the generation of GFP-tagged reagents on a genome-wide scale with diverse potential applications. ..
  9. Liu N, Han H, Lasko P. Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR. Genes Dev. 2009;23:2742-52 pubmed publisher
    ..Taken together, our data support the conclusion that Vas promotes germ cell differentiation by directly activating mei-P26 translation in early-stage committed cells. ..

More Information


  1. Paunola E, Mattila P, Lappalainen P. WH2 domain: a small, versatile adapter for actin monomers. FEBS Lett. 2002;513:92-7 pubmed
    ..motif, that is found in many different regulators of the actin cytoskeleton, including the beta-thymosins, ciboulot, WASP (Wiskott Aldrich syndrome protein), verprolin/WIP (WASP-interacting protein), Srv2/CAP (adenylyl cyclase-..
  2. Aguda A, Xue B, Irobi E, Pr at T, Robinson R. The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins. Structure. 2006;14:469-76 pubmed publisher
    ..WH2/betaT motif repetition (typified by ciboulot) or combination with nonrelated domains (as found in N-WASP) results in proteins that yield their actin to ..