CIA30

Summary

Gene Symbol: CIA30
Description: Complex I intermediate-associated protein, 30 kDa
Alias: CG7598, CI30, Dmel\CG7598, dCIA30, complex I intermediate-associated protein, 30 kDa, CG7598-PA, CIA30-PA, complex I intermediate- associate protein 30, complex I intermediate-associated protein 30
Species: fruit fly

Top Publications

  1. Cho J, Hur J, Graniel J, Benzer S, Walker D. Expression of yeast NDI1 rescues a Drosophila complex I assembly defect. PLoS ONE. 2012;7:e50644 pubmed publisher
    ..We show that CG7598 (dCIA30), the Drosophila homolog of human complex I assembly factor Ndufaf1, is necessary for proper complex I assembly...
  2. Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, et al. The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell. 2014;158:1293-1308 pubmed publisher
    ..Defects in mitochondrial activity in ft mutants are independent of Hippo and PCP signaling and are reminiscent of the Warburg effect. ..
  3. Barry W, Thummel C. The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults. elife. 2016;5: pubmed publisher
    ..These findings establish an animal model for MODY1 and define a developmental reprogramming of metabolism to support the energetic needs of the mature animal. ..