Gene Symbol: CG5103
Alias: Dmel\CG5103, CG5103, CG5103-PA
Species: fruit fly
Srinivasula S, Datta P, Kobayashi M, Wu J, Fujioka M, Hegde R, et al
. sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr Biol. 2002;12:125-30 pubmed
..These findings point to conservation in the structure and function of the IAP-inhibitory proteins across species and suggest the existence of other family members. ..
Wing J, Karres J, Ogdahl J, Zhou L, Schwartz L, Nambu J. Drosophila sickle is a novel grim-reaper cell death activator. Curr Biol. 2002;12:131-5 pubmed
..However, sickle strongly enhanced the eye cell death induced by expression of either an r/grim chimera or reaper. ..
Wu J, Nguyen N, Aghazarian M, Tan Y, Sevrioukov E, Mabuchi M, et al
. grim promotes programmed cell death of Drosophila microchaete glial cells. Mech Dev. 2010;127:407-17 pubmed publisher
..PCD of microchaete glial cells represents an exceptional opportunity to study the mitochondrial proapoptotic process induced by Grim. ..
Tan Y, Yamada Mabuchi M, Arya R, St Pierre S, Tang W, Tosa M, et al
. Coordinated expression of cell death genes regulates neuroblast apoptosis. Development. 2011;138:2197-206 pubmed publisher
..The overlapping activity of these multiple cell death genes suggests that the coordinated regulation of their expression provides flexibility in this crucial developmental process. ..
Nikulova A, Favorov A, Sutormin R, Makeev V, Mironov A. CORECLUST: identification of the conserved CRM grammar together with prediction of gene regulation. Nucleic Acids Res. 2012;40:e93 pubmed publisher
..Compared with related methods, CORECLUST shows better performance at identification of CRMs conferring muscle-specific gene expression in vertebrates and early-developmental CRMs in Drosophila. ..