CG3326

Summary

Gene Symbol: CG3326
Description: CG3326
Alias: DmCG3326, Dmel\CG3326, CG3326, CG3326-PA, CG3326-PB, Dm-fidgetin, fidgetin_DROME
Species: fruit fly

Top Publications

  1. Kammermeier L, Spring J, Stierwald M, Burgunder J, Reichert H. Identification of the Drosophila melanogaster homolog of the human spastin gene. Dev Genes Evol. 2003;213:412-5 pubmed
    ..Given this nervous system-specific expression, it will be important to determine if Drosophila spastin loss-of-function mutations also lead to neurodegeneration. ..
  2. Zhang D, Rogers G, Buster D, Sharp D. Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes. J Cell Biol. 2007;177:231-42 pubmed
    ..Collectively, these findings reveal novel and significant roles for microtubule severing within the spindle and broaden our understanding of the molecular machinery used to move chromosomes. ..
  3. Tao J, Feng C, Rolls M. The microtubule-severing protein fidgetin acts after dendrite injury to promote their degeneration. J Cell Sci. 2016;129:3274-81 pubmed publisher
    ..However, we identified a fidgetin-dependent increase in microtubule dynamics in severed dendrites. We conclude that fidgetin acts after injury to promote disassembly of microtubules in dendrites severed from the cell body. ..