Gene Symbol: CCHa1
Alias: CCH1, CCM, CG14358, Dm-CCHa1, Dmel\CG14358, CCHamide-1, CCHa1-PB, CCHamide, CCHamide 1, CCHamide1, CG14358-PB, Drm-CCHamide-1
Species: fruit fly
Hansen K, Hauser F, Williamson M, Weber S, Grimmelikhuijzen C. The Drosophila genes CG14593 and CG30106 code for G-protein-coupled receptors specifically activated by the neuropeptides CCHamide-1 and CCHamide-2. Biochem Biophys Res Commun. 2011;404:184-9 pubmed publisher
Recently, a novel neuropeptide, CCHamide, was discovered in the silkworm Bombyx mori (L. Roller et al., Insect Biochem. Mol. Biol. 38 (2008) 1147-1157)...
Reiher W, Shirras C, Kahnt J, Baumeister S, Isaac R, Wegener C. Peptidomics and peptide hormone processing in the Drosophila midgut. J Proteome Res. 2011;10:1881-92 pubmed publisher
..DH(31), CCHamide1 and CCHamide2 are biochemically characterized for the first time...
Farhan A, Gulati J, Groβe Wilde E, Vogel H, Hansson B, Knaden M. The CCHamide 1 receptor modulates sensory perception and olfactory behavior in starved Drosophila. Sci Rep. 2013;3:2765 pubmed publisher
..In addition it revealed that the CCHamide-1 receptor is another important factor governing starvation-induced olfactory modifications.
Li S, Torre Muruzabal T, Søgaard K, Ren G, Hauser F, Engelsen S, et al
. Expression patterns of the Drosophila neuropeptide CCHamide-2 and its receptor may suggest hormonal signaling from the gut to the brain. PLoS ONE. 2013;8:e76131 pubmed publisher
The insect neuropeptides CCHamide-1 and -2 are recently discovered peptides that probably occur in all arthropods...
Veenstra J, Ida T. More Drosophila enteroendocrine peptides: Orcokinin B and the CCHamides 1 and 2. Cell Tissue Res. 2014;357:607-21 pubmed publisher
Antisera to orcokinin B, CCHamide 1, and CCHamide 2 recognize enteroendocrine cells in the midgut of the fruitfly Drosophila melanogaster and its larvae...
Ren G, Hauser F, Rewitz K, Kondo S, Engelbrecht A, Didriksen A, et al
. CCHamide-2 Is an Orexigenic Brain-Gut Peptide in Drosophila. PLoS ONE. 2015;10:e0133017 pubmed publisher
The neuroendocrine peptides CCHamide-1 and -2, encoded by the genes ccha1 and -2, are produced by endocrine cells in the midgut and by neurons in the brain of Drosophila melanogaster...