Gene Symbol: ATPsynD
Description: ATP synthase, subunit D
Alias: ATP syn-d, ATPQ, ATPsyn-D, ATPsyn-d, ATPsyn-delta, CG6030, Dmel\CG6030, ATP synthase, subunit D, ATP synthase D chain, ATP synthase chain D, ATP synthase subunits d, ATP synthase, subunit d, ATP synthase,d, ATPase synthase, subunit d, ATPsyn-d, ATPsynD-PA, ATPsynD-PB, ATPsynD-PC, CG6030-PA, CG6030-PB, CG6030-PC, F0/F1 ATP synthase D
Species: fruit fly
Teixeira F, Sanchez C, Hurd T, Seifert J, Czech B, Preall J, et al
. ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation. Nat Cell Biol. 2015;17:689-96 pubmed publisher
..Taken together, our results suggest that ATP synthase-dependent crista maturation is a key developmental process required for differentiation independent of oxidative phosphorylation. ..
Ryder E, Blows F, Ashburner M, Bautista Llacer R, Coulson D, Drummond J, et al
. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics. 2004;167:797-813 pubmed
..In addition, a further 37,000 deletions, selectable by molecular screening, may be generated. We are now using the collection to generate a second-generation deficiency kit that is precisely mapped to the genome sequence. ..
Domanitskaya E, Liu H, Chen S, Kubli E. The hydroxyproline motif of male sex peptide elicits the innate immune response in Drosophila females. FEBS J. 2007;274:5659-68 pubmed
..We suggest that SP acts by chemical mimicry of sugar components of the bacterial cell wall. Thus, SP may induce the immune system via pattern recognition receptors. ..
Di Cara F, Duca E, Dunbar D, Cagney G, Heck M. Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila. J Cell Sci. 2013;126:4769-81 pubmed publisher
..As a consequence, invadolysin mutant larvae show lower energetic status and higher oxidative stress. Our data demonstrate an essential role for invadolysin in mitochondrial function that is crucial for normal development and survival. ..
Matthews B, Crews S. Drosophila center divider gene is expressed in CNS midline cells and encodes a developmentally regulated protein kinase orthologous to human TESK1. DNA Cell Biol. 1999;18:435-48 pubmed
..The unique sequence is conserved in Cdi, suggesting that Cdi/TESK1 represents a novel class of signaling proteins. ..
Liao T, Call G, Guptan P, Cespedes A, Marshall J, Yackle K, et al
. An efficient genetic screen in Drosophila to identify nuclear-encoded genes with mitochondrial function. Genetics. 2006;174:525-33 pubmed
..We have molecularly characterized six complementation groups and, surprisingly, each encodes a mitochondrial protein. Therefore, we believe our screen to be an efficient method for identifying genes with mitochondrial function. ..
Sesé M, Corominas M, Stocker H, Heino T, Hafen E, Serras F. The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye. J Cell Sci. 2006;119:5047-56 pubmed
..Our results reveal a critical interplay between the localization of molecules involved in epithelial organization and signal transduction. ..
Sun X, Wheeler C, Yolitz J, Laslo M, Alberico T, Sun Y, et al
. A mitochondrial ATP synthase subunit interacts with TOR signaling to modulate protein homeostasis and lifespan in Drosophila. Cell Rep. 2014;8:1781-1792 pubmed publisher
..Our data reveal a link among diet, mitochondria, and MAPK and TOR signaling in aging and stresses the importance of considering genetic background and diet composition in implementing interventions for promoting healthy aging. ..
Ivanov D, Escott Price V, Ziehm M, Magwire M, Mackay T, Partridge L, et al
. Longevity GWAS Using the Drosophila Genetic Reference Panel. J Gerontol A Biol Sci Med Sci. 2015;70:1470-8 pubmed publisher
..This analysis suggests that our understanding of the genetic basis of natural variation in lifespan from induced mutations is incomplete. ..