Gene Symbol: atms
Alias: Atms, CG2503, Dmel\CG2503, PAF, PAF1, Paf1, anon-WO0172774.113, anon-WO0172774.114, anon-WO0172774.116, l(3)01456, l(3)02466, l(3)rK509, antimeros, CG2503-PA, CG2503-PB, atms-PA, atms-PB
Species: fruit fly
Yokoyama R, Pannuti A, Ling H, Smith E, Lucchesi J. A plasmid model system shows that Drosophila dosage compensation depends on the global acetylation of histone H4 at lysine 16 and is not affected by depletion of common transcription elongation chromatin marks. Mol Cell Biol. 2007;27:7865-70 pubmed
Pircs K, Nagy P, Varga A, Venkei Z, Erdi B, Hegedus K, et al
. Advantages and limitations of different p62-based assays for estimating autophagic activity in Drosophila. PLoS ONE. 2012;7:e44214 pubmed publisher
Chen F, Woodfin A, Gardini A, Rickels R, Marshall S, Smith E, et al
. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. 2015;162:1003-15 pubmed publisher
..Here, we identify that Pol-II-associated factor 1 (PAF1) possesses an evolutionarily conserved function in metazoans in the regulation of promoter-proximal pausing...
Adelman K, Wei W, Ardehali M, Werner J, Zhu B, Reinberg D, et al
. Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Mol Cell Biol. 2006;26:250-60 pubmed
The Paf1 complex in yeast has been reported to influence a multitude of steps in gene expression through interactions with RNA polymerase II (Pol II) and chromatin-modifying complexes; however, it is unclear which of these many activities ..
Schaerlinger B, Launay J, Vonesch J, Maroteaux L. Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation. Dev Dyn. 2007;236:991-9 pubmed
Chicoine J, Benoit P, Gamberi C, Paliouras M, Simonelig M, Lasko P. Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Dev Cell. 2007;13:691-704 pubmed
..We conclude that Bic-C regulates expression of specific germline mRNAs by controlling their poly(A)-tail length. ..
Colas J, Launay J, Vonesch J, Hickel P, Maroteaux L. Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila. Mech Dev. 1999;87:77-91 pubmed
Buszczak M, Paterno S, Spradling A. Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny. Science. 2009;323:248-51 pubmed publisher
..Our findings suggest that inhibiting H2B ubiquitylation through scny represents a common mechanism within stem cells that is used to repress the premature expression of key differentiation genes, including Notch target genes. ..
Zhang J, Panicker L, Seigneur E, Lin L, House C, Morgan W, et al
. Cytoplasmic polyadenylation element binding protein is a conserved target of tumor suppressor HRPT2/CDC73. Cell Death Differ. 2010;17:1551-65 pubmed publisher
..in parathyroid cancer and the hyperparathyroidism-jaw tumor (HPT-JT) familial cancer syndrome, is part of the PAF1 transcriptional regulatory complex...