Gene Symbol: ASPP
Description: Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein
Alias: CG18375, Dmel\CG18375, dASPP, Ankyrin-repeat, SH3-domain, and Proline-rich-region containing protein, ASPP-PA, ASPP-PB, ASPP-PC, Ankyrin-repeat, SH3-domain and Proline-rich-region containing protein, CG18375-PA, CG18375-PB, CG18375-PC
Species: fruit fly

Top Publications

  1. Langton P, Colombani J, Aerne B, Tapon N. Drosophila ASPP regulates C-terminal Src kinase activity. Dev Cell. 2007;13:773-82 pubmed
    ..We have identified Drosophila Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein (dASPP) as a regulator of Drosophila Csk (dCsk) activity...
  2. Langton P, Colombani J, Chan E, Wepf A, Gstaiger M, Tapon N. The dASPP-dRASSF8 complex regulates cell-cell adhesion during Drosophila retinal morphogenesis. Curr Biol. 2009;19:1969-78 pubmed publisher
    ..We previously identified dASPP as a positive regulator of dCsk (Drosophila C-terminal Src kinase)...
  3. Bothma J, Magliocco J, Levine M. The snail repressor inhibits release, not elongation, of paused Pol II in the Drosophila embryo. Curr Biol. 2011;21:1571-7 pubmed publisher
  4. Chen P, Lee C, Weng Y, Tarn W, Tsao Y, Kuo P, et al. BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. RNA. 2013;19:208-18 pubmed publisher
    ..In summary, Drosophila and human BCAS2 share a similar function in RNA splicing, which affects cell viability. ..
  5. Zaessinger S, Zhou Y, Bray S, Tapon N, Djiane A. Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye. Development. 2015;142:1102-12 pubmed publisher
    ..domain protein RASSF8 through a WW domain-PPxY motif binding, and show that apical Magi recruits the RASSF8-ASPP complex during AJ remodeling in IOCs...
  6. Dimitriadi M, Sleigh J, Walker A, Chang H, Sen A, Kalloo G, et al. Conserved genes act as modifiers of invertebrate SMN loss of function defects. PLoS Genet. 2010;6:e1001172 pubmed publisher
  7. Zhang W, Cohen S. The Hippo pathway acts via p53 and microRNAs to control proliferation and proapoptotic gene expression during tissue growth. Biol Open. 2013;2:822-8 pubmed publisher
    ..These findings provide evidence that the Hippo pathway acts via several distinct routes to limit proliferation-induced apoptosis. ..