Gene Symbol: Arf102F
Description: ADP ribosylation factor at 102F
Alias: ARF2, ARFII, Arf102E, Arf2, Arf4, Arf5, CG11027, Dmel\CG11027, P40945, arf102F, arf4, dARFII, ADP ribosylation factor at 102F, ADP ribosylation factor 102F, ADP ribosylation factor II, Arf102F-PA, Arf102F-PB, CG11027-PA, CG11027-PB
Species: fruit fly

Top Publications

  1. Lee F, Stevens L, Hall L, Murtagh J, Kao Y, Moss J, et al. Characterization of class II and class III ADP-ribosylation factor genes and proteins in Drosophila melanogaster. J Biol Chem. 1994;269:21555-60 pubmed
    ..Recombinant dARF II and dARF III have biochemical and immunological properties similar to those of human ARF5 (hARF5) and hARF6, respectively...
  2. Pasqualato S, Renault L, Cherfils J. Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication. EMBO Rep. 2002;3:1035-41 pubmed
    ..We review available genomic sequences and functional data from this perspective, and identify a novel subfamily that we call Arl8. ..
  3. Kametaka S, Kametaka A, Yonekura S, Haruta M, Takenoshita S, Goto S, et al. AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster. J Cell Sci. 2012;125:634-48 pubmed publisher
    ..These results suggest that AP-1 and Aftiphilin are cooperatively involved in the intracellular trafficking of Notch during eye development in Drosophila. ..
  4. Podemski L, Sousa Neves R, Marsh J, Locke J. Molecular mapping of deletion breakpoints on chromosome 4 of Drosophila melanogaster. Chromosoma. 2004;112:381-8 pubmed
    ..This will substantially reduce the amount of DHPLC analysis required to match each mutation to a predicted transcript on chromosome 4. ..
  5. Costello J, Dalkilic M, Beason S, Gehlhausen J, Patwardhan R, Middha S, et al. Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function. Genome Biol. 2009;10:R97 pubmed publisher
    ..melanogaster. The network enables the exploration, mining, and reanalysis of experimental data, as well as the interpretation of new data. The inferred annotations provide testable hypotheses of previously uncharacterized genes. ..
  6. Sepp K, Hong P, Lizarraga S, Liu J, Mejia L, Walsh C, et al. Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genet. 2008;4:e1000111 pubmed publisher
    ..Collectively, our results showed that RNAi phenotypes in primary neural culture can parallel in vivo phenotypes, and the screening technique can be used to identify many new genes that have important functions in the nervous system. ..
  7. Kametaka S, Sawada N, Bonifacino J, Waguri S. Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster. J Cell Sci. 2010;123:460-71 pubmed publisher
  8. Christis C, Munro S. The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2. J Cell Biol. 2012;196:327-35 pubmed publisher
    ..We validate this with the Drosophila melanogaster Arf1 orthologue (Arf79F) and the related class II Arf (Arf102F), which showed a similar pattern of effector binding...
  9. Armbruster K, Luschnig S. The Drosophila Sec7 domain guanine nucleotide exchange factor protein Gartenzwerg localizes at the cis-Golgi and is essential for epithelial tube expansion. J Cell Sci. 2012;125:1318-28 pubmed publisher
    ..Thus, garz might regulate epithelial tube morphogenesis and secretion by controlling the rate of trafficking of COPI vesicles. ..

More Information


  1. Lee D, Rodrigues F, Yu C, Swan M, Harris T. PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila. PLoS ONE. 2015;10:e0142562 pubmed publisher
    ..By analyzing GFP-tagged Arf and Arf-like small G proteins, we found that Arf1-GFP, Arf6-GFP and Arl4-GFP, but not Arf4-GFP, localized to furrows...
  2. Humphreys D, Liu T, Davidson A, Hume P, Koronakis V. The Drosophila Arf1 homologue Arf79F is essential for lamellipodium formation. J Cell Sci. 2012;125:5630-5 pubmed publisher
    ..Our data indicate that the Class I Arf GTPase is a central component in WRC-driven lamellipodium formation. ..