APC7

Summary

Gene Symbol: APC7
Description: Anaphase Promoting Complex subunit 7
Alias: Apc7, CG14444, Dmel\CG14444, anaphase promoting complex subunit 7, APC7-PA, APC7-PB, CG14444-PA, CG14444-PB, anaphase promoting complex 7
Species: fruit fly

Top Publications

  1. Pines M, Housden B, Bernard F, Bray S, Röper K. The cytolinker Pigs is a direct target and a negative regulator of Notch signalling. Development. 2010;137:913-22 pubmed publisher
  2. Harper J, Burton J, Solomon M. The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev. 2002;16:2179-206 pubmed
  3. Acquaviva C, Pines J. The anaphase-promoting complex/cyclosome: APC/C. J Cell Sci. 2006;119:2401-4 pubmed
  4. Pal M, Nagy O, Ménesi D, Udvardy A, Deak P. Structurally related TPR subunits contribute differently to the function of the anaphase-promoting complex in Drosophila melanogaster. J Cell Sci. 2007;120:3238-48 pubmed
    ..we demonstrate that the Drosophila APC/C associates with a new TPR protein, a genuine orthologue of the vertebrate Apc7 subunit that is not found in yeasts...
  5. Buttitta L, Katzaroff A, Edgar B. A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo. J Cell Biol. 2010;189:981-96 pubmed publisher
    ..These mechanisms are essential for proper development, as evading them leads to tissue outgrowths composed of dividing but terminally differentiated cells. ..
  6. Casad M, Yu L, Daniels J, Wolf M, Rockman H. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Mol Genet Genomics. 2012;287:351-60 pubmed publisher
    ..Alterations in Armadillo signaling during development lead to important changes in the size and function of the adult heart. ..
  7. Magwire M, Fabian D, Schweyen H, Cao C, Longdon B, Bayer F, et al. Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogaster. PLoS Genet. 2012;8:e1003057 pubmed publisher
    ..Our data suggest that selection for resistance to infectious disease can increase genetic variation by increasing the frequency of major-effect alleles, and this has resulted in a simple genetic basis to variation in virus resistance. ..