Gene Symbol: APC4
Description: Anaphase Promoting Complex subunit 4
Alias: CG32707, CG4350, Dmel\CG32707, anaphase promoting complex subunit 4, APC4-PA, APC4-PC, CG32707-PA, CG32707-PC, anaphase promoting complex 4
Species: fruit fly

Top Publications

  1. Buttitta L, Katzaroff A, Edgar B. A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo. J Cell Biol. 2010;189:981-96 pubmed publisher
    ..These mechanisms are essential for proper development, as evading them leads to tissue outgrowths composed of dividing but terminally differentiated cells. ..
  2. Kunda P, Rodrigues N, Moeendarbary E, Liu T, Ivetic A, Charras G, et al. PP1-mediated moesin dephosphorylation couples polar relaxation to mitotic exit. Curr Biol. 2012;22:231-6 pubmed publisher
    ..These data reveal a new role for the PP1-87B/Sds22 phosphatase, an important regulator of the metaphase-anaphase transition, in coupling moesin-dependent cell shape changes to mitotic exit. ..
  3. Mohd Sarip A, Lagarou A, Doyen C, van der Knaap J, Aslan U, Bezstarosti K, et al. Transcription-independent function of Polycomb group protein PSC in cell cycle control. Science. 2012;336:744-7 pubmed publisher
    ..Thus, PSC appears to mediate both developmental gene silencing and posttranslational control of mitosis. Direct regulation of cell cycle progression might be a crucial part of the PcG system's function in development and cancer. ..
  4. Mauri F, Reichardt I, Mummery Widmer J, Yamazaki M, Knoblich J. The conserved discs-large binding partner Banderuola regulates asymmetric cell division in Drosophila. Curr Biol. 2014;24:1811-25 pubmed publisher
    ..Bnd has an antioncogenic function that is redundant with Dlg, and the physical interaction between the two proteins is conserved in evolution. ..
  5. Harper J, Burton J, Solomon M. The anaphase-promoting complex: it's not just for mitosis any more. Genes Dev. 2002;16:2179-206 pubmed
  6. Acquaviva C, Pines J. The anaphase-promoting complex/cyclosome: APC/C. J Cell Sci. 2006;119:2401-4 pubmed