rpn7

Summary

Gene Symbol: rpn7
Description: 19S proteasome regulatory subunit Rpn7
Alias: 19S proteasome regulatory subunit Rpn7
Species: fission yeast

Top Publications

  1. Sha Z, Yen H, Scheel H, Suo J, Hofmann K, Chang E. Isolation of the Schizosaccharomyces pombe proteasome subunit Rpn7 and a structure-function study of the proteasome-COP9-initiation factor domain. J Biol Chem. 2007;282:32414-23 pubmed
    ..In this study, we isolated another PCI proteasome subunit, Rpn7, as a high copy suppressor that rescued the proteasome defects in yin6 null cells...
  2. Jossé L, Harley M, Pires I, Hughes D. Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis. Biochem J. 2006;393:303-9 pubmed
    ..These findings show that DSS1 has an evolutionarily conserved role as a regulator of proteasome function and suggest that DSS1 may provide a link between BRCA2 and ubiquitin-mediated proteolysis in human cells. ..
  3. Cabrera R, Sha Z, Vadakkan T, Otero J, Kriegenburg F, Hartmann Petersen R, et al. Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe. Mol Biol Cell. 2010;21:3125-36 pubmed publisher
    ..These data suggest that proteasomes display Arc3-dependent mobility in the cell, and mobile proteasomes can efficiently access substrates throughout the cell, allowing them to effectively regulate cell-compartment-specific activities. ..