Gene Symbol: rnh1
Description: putative ribonuclease H Rnh1
Species: fission yeast

Top Publications

  1. Parajuli S, Teasley D, Murali B, Jackson J, Vindigni A, Stewart S. Human ribonuclease H1 resolves R-loops and thereby enables progression of the DNA replication fork. J Biol Chem. 2017;292:15216-15224 pubmed publisher
    ..Here, using DNA fiber analysis, we demonstrate that human ribonuclease H1 (RNH1) plays an important role in replication fork movement in the mammalian nucleus by resolving R-loops...
  2. Legros P, Malapert A, Niinuma S, Bernard P, Vanoosthuyse V. RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes. PLoS Genet. 2014;10:e1004794 pubmed publisher
    ..2 and Sen1. Our data challenge the idea that a processive RNA polymerase hinders the binding of condensin and suggest that transcription-associated topological stress could in some circumstances facilitate the association of condensin. ..