Gene Symbol: mes1
Description: protein Mes1
Alias: protein Mes1
Species: fission yeast

Top Publications

  1. Izawa D, Goto M, Yamashita A, Yamano H, Yamamoto M. Fission yeast Mes1p ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p. Nature. 2005;434:529-33 pubmed
    ..However, fission yeast Mes1p is essential for MII but dispensable for mitosis. The mes1-B44 mutant arrests before MII...
  2. Kimata Y, Trickey M, Izawa D, Gannon J, Yamamoto M, Yamano H. A mutual inhibition between APC/C and its substrate Mes1 required for meiotic progression in fission yeast. Dev Cell. 2008;14:446-54 pubmed publisher
    ..Here we show that fission yeast Mes1 is a substrate of the APC/C as well as an inhibitor, allowing autoregulation of the APC/C in meiosis...
  3. Xu X, Zhang Z, Gu L, Wang F. [BTLA Characterization and its association with disease progression in patients with chronic HIV-1 infection.]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009;25:1158-60 pubmed
    ..Manipulation of BTLA inhibitory pathway may present an alternative strategy for overcoming immune activation for this disease. ..
  4. Arata M, Sato M, Yamashita A, Yamamoto M. The RNA-binding protein Spo5 promotes meiosis II by regulating cyclin Cdc13 in fission yeast. Genes Cells. 2014;19:225-38 pubmed publisher
  5. Kimata Y, Kitamura K, Fenner N, Yamano H. Mes1 controls the meiosis I to meiosis II transition by distinctly regulating the anaphase-promoting complex/cyclosome coactivators Fzr1/Mfr1 and Slp1 in fission yeast. Mol Biol Cell. 2011;22:1486-94 pubmed publisher
    ..We previously showed that the fission yeast meiosis-specific protein Mes1 binds to a coactivator and inhibits APC/C; however, regulation of the Mes1-mediated APC/C inhibition remains ..
  6. Aoi Y, Arai K, Miyamoto M, Katsuta Y, Yamashita A, Sato M, et al. Cuf2 boosts the transcription of APC/C activator Fzr1 to terminate the meiotic division cycle. EMBO Rep. 2013;14:553-60 pubmed publisher
    ..fzr1? also enters a third nuclear division. Thus, Cuf2 ensures termination of the M-phase cycle by boosting Fzr1 expression to generate functional gametes. ..