Gene Symbol: isa2
Description: Fe-sulfur protein Isa2
Alias: Fe-sulfur protein Isa2
Species: fission yeast

Top Publications

  1. Wu G, Mansy S, Hemann C, Hille R, Surerus K, Cowan J. Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1. J Biol Inorg Chem. 2002;7:526-32 pubmed
    ..Electronic supplementary material to this paper, containing Mössbauer and UV-visible spectra for mutant Isa1 proteins, can be obtained by using the Springer Link server located at ..
  2. Kim K, Chung W, Kim H, Lee K, Roe J. Monothiol glutaredoxin Grx5 interacts with Fe-S scaffold proteins Isa1 and Isa2 and supports Fe-S assembly and DNA integrity in mitochondria of fission yeast. Biochem Biophys Res Commun. 2010;392:467-72 pubmed publisher
    ..Examination of other scaffold and chaperone genes revealed that isa2(+), but not isu1(+) and ssc1(+), complemented the growth phenotype of Deltagrx5 mutant as isa1(+) did, partly ..
  3. Brancaccio D, Gallo A, Mikolajczyk M, Zovo K, Palumaa P, Novellino E, et al. Formation of [4Fe-4S] clusters in the mitochondrial iron-sulfur cluster assembly machinery. J Am Chem Soc. 2014;136:16240-50 pubmed publisher
    ..These findings imply that such heterodimeric complex is the functional unit in mitochondria receiving [2Fe-2S] clusters from hGRX5 and assembling [4Fe-4S] clusters before their transfer to the final target apo proteins. ..