isa2

Summary

Gene Symbol: isa2
Description: Fe-sulfur protein Isa2
Alias: Fe-sulfur protein Isa2
Species: fission yeast

Top Publications

  1. Wu G, Mansy S, Hemann C, Hille R, Surerus K, Cowan J. Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1. J Biol Inorg Chem. 2002;7:526-32 pubmed
    ..Electronic supplementary material to this paper, containing Mössbauer and UV-visible spectra for mutant Isa1 proteins, can be obtained by using the Springer Link server located at http://dx.doi.org/10.1007/s00775-001-0330-2. ..
  2. Kim K, Chung W, Kim H, Lee K, Roe J. Monothiol glutaredoxin Grx5 interacts with Fe-S scaffold proteins Isa1 and Isa2 and supports Fe-S assembly and DNA integrity in mitochondria of fission yeast. Biochem Biophys Res Commun. 2010;392:467-72 pubmed publisher
    ..Examination of other scaffold and chaperone genes revealed that isa2(+), but not isu1(+) and ssc1(+), complemented the growth phenotype of Deltagrx5 mutant as isa1(+) did, partly ..
  3. Brancaccio D, Gallo A, Mikolajczyk M, Zovo K, Palumaa P, Novellino E, et al. Formation of [4Fe-4S] clusters in the mitochondrial iron-sulfur cluster assembly machinery. J Am Chem Soc. 2014;136:16240-50 pubmed publisher
    ..These findings imply that such heterodimeric complex is the functional unit in mitochondria receiving [2Fe-2S] clusters from hGRX5 and assembling [4Fe-4S] clusters before their transfer to the final target apo proteins. ..