Gene Symbol: imp1
Description: importin alpha
Alias: importin alpha
Species: fission yeast
Chen X, Du X, Liu J, Balasubramanian M, Balasundaram D. Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis. Yeast. 2004;21:495-509 pubmed
..Further genetic analysis revealed that one of the nucleoporin genes, nup40, and another gene, SPCC1322.06, encoding a putative importin-beta/Cse1p superfamily protein may have a spindle checkpoint function. ..
Umeda M, Izaddoost S, Cushman I, Moore M, Sazer S. The fission yeast Schizosaccharomyces pombe has two importin-alpha proteins, Imp1p and Cut15p, which have common and unique functions in nucleocytoplasmic transport and cell cycle progression. Genetics. 2005;171:7-21 pubmed
..genes, but in fission yeast there are two: the previously characterized cut15 and the more recently identified imp1. Like other importin-alpha family members, Imp1p supports nuclear protein import in vitro...
Khan M, Jacques J, Beaudoin J, LabbÃ© S. Characterization of the nuclear import mechanism of the CCAAT-regulatory subunit Php4. PLoS ONE. 2014;9:e110721 pubmed publisher
..Under low-iron conditions, a functional GFP-Php4 protein is only partly targeted to the nucleus in imp1Î” and sal3Î” mutant cells...
Asadi F, Chakraborty B, Karagiannis J. Latrunculin A-Induced Perturbation of the Actin Cytoskeleton Mediates Pap1p-Dependent Induction of the Caf5p Efflux Pump in Schizosaccharomyces pombe. G3 (Bethesda). 2017;7:723-730 pubmed publisher
Lucena R, Dephoure N, Gygi S, Kellogg D, Tallada V, Daga R, et al
. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. J Cell Biol. 2015;209:387-402 pubmed publisher
..We show that, during anaphase B, Imp1-mediated transport of the AAA-ATPase Cdc48 protein at the MMD allows this disassembly factor to localize at the ..
Tallada V, Daga R, Palomeque C, Garzón A, Jimenez J. Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects. Yeast. 2002;19:1139-51 pubmed
..L41, S6, S11, S17 and the PolyA-Binding Protein PABP), protein degradation (UBI3), nucleolar rRNA expression (fib, imp1, dbp2), cell cytoskeleton (act1) and glycolysis (pfk1)...
Sistla S, Pang J, Wang C, Balasundaram D. Multiple conserved domains of the nucleoporin Nup124p and its orthologs Nup1p and Nup153 are critical for nuclear import and activity of the fission yeast Tf1 retrotransposon. Mol Biol Cell. 2007;18:3692-708 pubmed
..Although full-length Nup1p or Nup153 does not complement Nup124p, the functionality of their conserved domains with reference to Tf1 activity suggests that these three proteins evolved from a common ancestor. ..