Gene Symbol: chs2
Description: chitin synthase-like protein 2
Alias: SPBC1734.17, chitin synthase-like protein 2
Species: fission yeast

Top Publications

  1. Martín García R, Duran A, Valdivieso M. In Schizosaccharomyces pombe chs2p has no chitin synthase activity but is related to septum formation. FEBS Lett. 2003;549:176-80 pubmed
    ..In Schizosaccharomyces pombe the chs2(+) gene codes for a protein with significant similarity to CS enzymes, but lacking most of the residues considered ..
  2. Martín García R, Valdivieso M. The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring. J Cell Sci. 2006;119:2768-79 pubmed
    ..In synchronous cultures, chs2Delta cells exhibit a delay in septation with respect to the control strain. All these results show that Chs2p participates in the correct functioning of the medial ring. ..
  3. Matsuo Y, Tanaka K, Nakagawa T, Matsuda H, Kawamukai M. Genetic analysis of chs1+ and chs2+ encoding chitin synthases from Schizosaccharomyces pombe. Biosci Biotechnol Biochem. 2004;68:1489-99 pubmed
    To explore the function of chitin in Schizosaccharomyces pombe, we have cloned chs1+ and chs2+, encoding putative chitin synthases, based on sequences in the Sanger Centre database. The synthetic lethal phenotype of the S...
  4. Pollard L, Onishi M, Pringle J, Lord M. Fission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis. Mol Biol Cell. 2012;23:2433-44 pubmed publisher
    ..We suggest that the proposed evolution of animal transglutaminase cross-linking activity from ancestral bacterial thiol proteases was accompanied by the emergence of a subclass whose function does not depend on enzymatic activity. ..