Gene Symbol: atg8
Description: autophagy-associated protein Atg8
Alias: autophagy-associated protein Atg8
Species: fission yeast
Kohda T, Tanaka K, Konomi M, Sato M, Osumi M, Yamamoto M. Fission yeast autophagy induced by nitrogen starvation generates a nitrogen source that drives adaptation processes. Genes Cells. 2007;12:155-70 pubmed
..We propose that fission yeast autophagy functions to supply nitrogen and is activated when cells cannot access exogenous nitrogen, thus ensuring that they can adapt and subsequently propagate. ..
Mukaiyama H, Kajiwara S, Hosomi A, Giga Hama Y, Tanaka N, Nakamura T, et al
. Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation. Microbiology. 2009;155:3816-26 pubmed publisher
..In this study, we show that processing of GFP-tagged Atg8 can serve as a marker for autophagy in the fission yeast Schizosaccharomyces pombe...
Mikawa T, Kanoh J, Ishikawa F. Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance. Genes Cells. 2010;15:229-42 pubmed publisher
..vps1? was sensitive to osmotic stress, high concentrations of Ca(2+) and Fe(2+). Interestingly, the deletion of atg8(+), a gene essential for the autophagy pathway, exhibited strong genetic interactions with vps1?...
Sun L, Li M, Suo F, Liu X, Shen E, Yang B, et al
. Global analysis of fission yeast mating genes reveals new autophagy factors. PLoS Genet. 2013;9:e1003715 pubmed publisher
..Our study sheds new light on the evolutionary diversity of the autophagy machinery and establishes the fission yeast as a useful model for dissecting the mechanisms of autophagy...
Su Y, Chen C, Huang L, Yan J, Huang Y. Schizosaccharomyces pombe Homologs of Human DJ-1 Are Stationary Phase-Associated Proteins That Are Involved in Autophagy and Oxidative Stress Resistance. PLoS ONE. 2015;10:e0143888 pubmed publisher
..Our results firmly establish that S. pombe homologs of DJ-1 are stationary-phase associated proteins and are likely involved in autophagy and antioxidant defense in stationary phase of S. pombe cells. ..
Takeda K, Yoshida T, Kikuchi S, Nagao K, Kokubu A, Pluskal T, et al
. Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast. Proc Natl Acad Sci U S A. 2010;107:3540-5 pubmed publisher
..Proteasome and autophagy are thus collaborative to support the lifespan of S. pombe G0 phase. ..