Gene Symbol: arc5
Description: ARP2/3 actin-organizing complex subunit Arc5
Alias: arc15, ARP2/3 actin-organizing complex subunit Arc5
Species: fission yeast
Skau C, Courson D, Bestul A, Winkelman J, Rock R, Sirotkin V, et al
. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. J Biol Chem. 2011;286:26964-77 pubmed publisher
..Therefore, fimbrin Fim1 has diverse roles as both a filament "gatekeeper" and as a filament cross-linker. ..
Encinar del Dedo J, Idrissi F, Arnaiz Pita Y, James M, Dueñas Santero E, Orellana Muñoz S, et al
. Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast. Traffic. 2014;15:1122-42 pubmed publisher
..Altogether, our work defines a novel endocytic functional module, which probably couples the endocytic coat to the actin module. ..
Dudin O, BendezÃº F, Groux R, Laroche T, Seitz A, Martin S. A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast. J Cell Biol. 2015;208:897-911 pubmed publisher
..Thus, the fusion focus focalizes cell wall dissolution within a broader cell wall synthesis zone to shift from cell growth to cell fusion. ..
Nolen B, Pollard T. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. J Biol Chem. 2008;283:26490-8 pubmed publisher
..Truncation of the N terminus of ARPC5, the smallest subunit in the complex, increased the yield of Arp2Delta Arp2/3 complex during purification but did not compromise nucleation activity of the full Arp2/3 complex. ..
Sirotkin V, Berro J, Macmillan K, Zhao L, Pollard T. Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast. Mol Biol Cell. 2010;21:2894-904 pubmed publisher
Basu R, Chang F. Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosis. Curr Biol. 2011;21:905-16 pubmed publisher
..This switch may be activated in at least two ways, through a dip1p-dependent mechanism and through contact with another endocytic vesicle. ..
Pelham R, Chang F. Actin dynamics in the contractile ring during cytokinesis in fission yeast. Nature. 2002;419:82-6 pubmed
..Our studies show that cytokinesis is a more dynamic process than previously thought and provide a perspective on the mechanism of cell division. ..