Gene Symbol: arc5
Description: ARP2/3 actin-organizing complex subunit Arc5
Alias: arc15, ARP2/3 actin-organizing complex subunit Arc5
Species: fission yeast

Top Publications

  1. Skau C, Courson D, Bestul A, Winkelman J, Rock R, Sirotkin V, et al. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. J Biol Chem. 2011;286:26964-77 pubmed publisher
    ..Therefore, fimbrin Fim1 has diverse roles as both a filament "gatekeeper" and as a filament cross-linker. ..
  2. Encinar del Dedo J, Idrissi F, Arnaiz Pita Y, James M, Dueñas Santero E, Orellana Muñoz S, et al. Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast. Traffic. 2014;15:1122-42 pubmed publisher
    ..Altogether, our work defines a novel endocytic functional module, which probably couples the endocytic coat to the actin module. ..
  3. Dudin O, Bendezú F, Groux R, Laroche T, Seitz A, Martin S. A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast. J Cell Biol. 2015;208:897-911 pubmed publisher
    ..Thus, the fusion focus focalizes cell wall dissolution within a broader cell wall synthesis zone to shift from cell growth to cell fusion. ..
  4. Nolen B, Pollard T. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. J Biol Chem. 2008;283:26490-8 pubmed publisher
    ..Truncation of the N terminus of ARPC5, the smallest subunit in the complex, increased the yield of Arp2Delta Arp2/3 complex during purification but did not compromise nucleation activity of the full Arp2/3 complex. ..
  5. Sirotkin V, Berro J, Macmillan K, Zhao L, Pollard T. Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast. Mol Biol Cell. 2010;21:2894-904 pubmed publisher
  6. Basu R, Chang F. Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosis. Curr Biol. 2011;21:905-16 pubmed publisher
    ..This switch may be activated in at least two ways, through a dip1p-dependent mechanism and through contact with another endocytic vesicle. ..
  7. Pelham R, Chang F. Actin dynamics in the contractile ring during cytokinesis in fission yeast. Nature. 2002;419:82-6 pubmed
    ..Our studies show that cytokinesis is a more dynamic process than previously thought and provide a perspective on the mechanism of cell division. ..