Gene Symbol: yjjG
Description: dUMP phosphatase
Alias: ECK4365, JW4336
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Itsko M, Schaaper R. The dgt gene of Escherichia coli facilitates thymine utilization in thymine-requiring strains. Mol Microbiol. 2011;81:1221-32 pubmed publisher
    ..Blockage of the alternative yjjG (dUMP phosphatase) pathway for deoxyribose-1-phosphate generation greatly exacerbated the severity of thymine ..
  2. Uerkvitz W, Karlstrom O, Munch Petersen A. A deoxyuridine monophosphate phosphatase detected in mutants of Escherichia coli lacking alkaline phosphatase and 5'-nucleotidase. Mol Gen Genet. 1973;121:337-46 pubmed
  3. Weiss B. YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. J Bacteriol. 2007;189:2186-9 pubmed
    ..The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium.
  4. Titz B, Hauser R, Engelbrecher A, Uetz P. The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo. FEMS Microbiol Lett. 2007;270:49-57 pubmed
    ..The Escherichia coli nucleotide phosphatase YjjG (B4374, JW4336) functions as a house-cleaning phosphatase in vivo...
  5. Han K, Park J, Seo H, Ahn K, Lee J. Multiple stressor-induced proteome responses of Escherichia coli BL21(DE3). J Proteome Res. 2008;7:1891-903 pubmed publisher
    ..The quantitative and systematic proteome analyses that we have performed provide more detailed information on E. coli BL21(DE3), a widely used host strain for recombinant protein overexpression. ..
  6. Proudfoot M, Kuznetsova E, Brown G, Rao N, Kitagawa M, Mori H, et al. General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG. J Biol Chem. 2004;279:54687-94 pubmed
    ..coli proteins, SurE, YfbR, and YjjG, that belong to different enzyme superfamilies: SurE-like family, HD domain family (YfbR), and haloacid ..