Gene Symbol: yjjG
Description: dUMP phosphatase
Alias: ECK4365, JW4336
Species: Escherichia coli str. K-12 substr. MG1655
Itsko M, Schaaper R. The dgt gene of Escherichia coli facilitates thymine utilization in thymine-requiring strains. Mol Microbiol. 2011;81:1221-32 pubmed publisher
..Blockage of the alternative yjjG (dUMP phosphatase) pathway for deoxyribose-1-phosphate generation greatly exacerbated the severity of thymine ..
Uerkvitz W, Karlstrom O, Munch Petersen A. A deoxyuridine monophosphate phosphatase detected in mutants of Escherichia coli lacking alkaline phosphatase and 5'-nucleotidase. Mol Gen Genet. 1973;121:337-46 pubmed
Weiss B. YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. J Bacteriol. 2007;189:2186-9 pubmed
..The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium.
Titz B, Hauser R, Engelbrecher A, Uetz P. The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo. FEMS Microbiol Lett. 2007;270:49-57 pubmed
..The Escherichia coli nucleotide phosphatase YjjG (B4374, JW4336) functions as a house-cleaning phosphatase in vivo...
Han K, Park J, Seo H, Ahn K, Lee J. Multiple stressor-induced proteome responses of Escherichia coli BL21(DE3). J Proteome Res. 2008;7:1891-903 pubmed publisher
..The quantitative and systematic proteome analyses that we have performed provide more detailed information on E. coli BL21(DE3), a widely used host strain for recombinant protein overexpression. ..
Proudfoot M, Kuznetsova E, Brown G, Rao N, Kitagawa M, Mori H, et al
. General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG. J Biol Chem. 2004;279:54687-94 pubmed
..coli proteins, SurE, YfbR, and YjjG, that belong to different enzyme superfamilies: SurE-like family, HD domain family (YfbR), and haloacid ..