Gene Symbol: yhdE
Description: dTTP/UTP pyrophosphatase; m(5)UTP/m(5)CTP/pseudo-UTP pyrophosphatase
Alias: ECK3236, JW3217, maf
Species: Escherichia coli str. K-12 substr. MG1655
Wachi M, Doi M, Ueda T, Ueki M, Tsuritani K, Nagai K, et al
. Sequence of the downstream flanking region of the shape-determining genes mreBCD of Escherichia coli. Gene. 1991;106:135-6 pubmed
..Two open reading frames (ORFs) were found, a 591-bp orfE and a 1467-bp orfF. Based on the sequence, it is suggested that the three mre genes (encoding the murein pathway), mreB, mreC and mreD, and these two ORFs possibly form an operon. ..
Minasov G, Teplova M, Stewart G, Koonin E, Anderson W, Egli M. Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP. Proc Natl Acad Sci U S A. 2000;97:6328-33 pubmed
..The Bacillus subtilis Maf protein is representative of a family of proteins that has homologs in many of the completely sequenced genomes ..
Tchigvintsev A, Tchigvintsev D, Flick R, Popović A, Dong A, Xu X, et al
. Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chem Biol. 2013;20:1386-98 pubmed publisher
..Overexpression of the Maf protein YhdE in E...
Jin J, Wu R, Zhu J, Yang S, Lei Z, Wang N, et al
. Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli. PLoS ONE. 2015;10:e0117823 pubmed publisher
b>YhdE, a Maf-like protein in Escherichia coli, exhibits nucleotide pyrophosphatase (PPase) activity, yet its cellular function remains unknown...