yeiR

Summary

Gene Symbol: yeiR
Description: Zn-stimulated GTPase involved in zinc homeostasis; mutants are cadmium and EDTA sensitive; Zn(2+) binding protein
Alias: ECK2167, JW2161
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Zheng Y, Roberts R, Kasif S. Segmentally variable genes: a new perspective on adaptation. PLoS Biol. 2004;2:E81 pubmed
    ..Discerning their function and identifying their binding partners may offer biologists new insights into the basic mechanisms of adaptation, context-dependent evolution, and the interaction between microbes and their environment. ..
  2. Haas C, Rodionov D, Kropat J, Malasarn D, Merchant S, De Crecy Lagard V. A subset of the diverse COG0523 family of putative metal chaperones is linked to zinc homeostasis in all kingdoms of life. BMC Genomics. 2009;10:470 pubmed publisher
    ..Additionally, Zur-dependent expression of COG0523 and putative paralogs of zinc-dependent proteins may represent a mechanism for hierarchal zinc distribution and zinc sparing in the face of inadequate zinc nutrition. ..
  3. Blaby Haas C, Flood J, Crécy Lagard V, Zamble D. YeiR: a metal-binding GTPase from Escherichia coli involved in metal homeostasis. Metallomics. 2012;4:488-97 pubmed publisher
    ..In this work we focused on the uncharacterized Escherichia coli protein YeiR by studying both the physiology of a yeiR mutant and the in vitro biochemical properties of YeiR expressed as a ..