Gene Symbol: yciM
Description: LPS regulatory protein; putative modulator of LpxC proteolysis
Alias: ECK1275, JW1272, lapB
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Prince C, Jia Z. An Unexpected Duo: Rubredoxin Binds Nine TPR Motifs to Form LapB, an Essential Regulator of Lipopolysaccharide Synthesis. Structure. 2015;23:1500-1506 pubmed publisher
    ..The essential protein LapB from Escherichia coli has recently been identified as a regulator of LPS synthesis...
  2. Hidaka M, Akiyama M, Horiuchi T. A consensus sequence of three DNA replication terminus sites on the E. coli chromosome is highly homologous to the terR sites of the R6K plasmid. Cell. 1988;55:467-75 pubmed
    ..In addition, all Ter active pUC-terC plasmids had a low copy number and were unstable in the host cells. ..
  3. Niba E, Naka Y, Nagase M, Mori H, Kitakawa M. A genome-wide approach to identify the genes involved in biofilm formation in E. coli. DNA Res. 2007;14:237-46 pubmed publisher
    ..of the nine mutants of function-unknown genes indicated that some of them, such as yfgA that genetically interacts with a periplasmic chaperone gene surA together with yciB and yciM, might be required for the integrity of outer membrane.
  4. Nicolaes V, El Hajjaji H, Davis R, Van der Henst C, Depuydt M, Leverrier P, et al. Insights into the function of YciM, a heat shock membrane protein required to maintain envelope integrity in Escherichia coli. J Bacteriol. 2014;196:300-9 pubmed publisher
    ..Strains lacking yciM were among the most sensitive strains of the mutant collection...
  5. Mahalakshmi S, Sunayana M, SaiSree L, Reddy M. yciM is an essential gene required for regulation of lipopolysaccharide synthesis in Escherichia coli. Mol Microbiol. 2014;91:145-57 pubmed publisher
    ..Here, we show that yciM, a gene encoding a tetratricopeptide repeat protein of unknown function, modulates LPS levels by negatively ..