yajC

Summary

Gene Symbol: yajC
Description: preprotein translocase subunit YajC
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Muller M, Koch H, Beck K, Schafer U. Protein traffic in bacteria: multiple routes from the ribosome to and across the membrane. Prog Nucleic Acid Res Mol Biol. 2001;66:107-57 pubmed
    ..into the SecYE translocon, a process that is strongly assisted by a couple of membrane proteins, SecG, SecD, SecF, YajC, and the proton gradient across the membrane...
  2. Duong F, Wickner W. Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme. EMBO J. 1997;16:2756-68 pubmed
    ..The proteins encoded by the secD operon--SecD, SecF and YajC--also form an integral membrane heterotrimeric complex (SecDFyajC)...
  3. Duong F, Wickner W. The SecDFyajC domain of preprotein translocase controls preprotein movement by regulating SecA membrane cycling. EMBO J. 1997;16:4871-9 pubmed
    ..coli preprotein translocase comprises a membrane-embedded hexameric complex of SecY, SecE, SecG, SecD, SecF and YajC (SecYEGDFyajC) and the peripheral ATPase SecA...
  4. Scotti P, Urbanus M, Brunner J, de Gier J, von Heijne G, van der Does C, et al. YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J. 2000;19:542-9 pubmed
    ..Previous work has also identified the peripherally associated SecA protein as well as the SecD, SecF and YajC inner membrane proteins as components of the translocase...
  5. Nouwen N, van der Laan M, Driessen A. SecDFyajC is not required for the maintenance of the proton motive force. FEBS Lett. 2001;508:103-6 pubmed
    ..The expression of this enzyme complex is repressed by growth on glucose media, the condition used to deplete SecDFyajC. These results demonstrate that SecDFyajC is not required for proton motive force-driven protein translocation...
  6. Nouwen N, Driessen A. SecDFyajC forms a heterotetrameric complex with YidC. Mol Microbiol. 2002;44:1397-405 pubmed
    ..SecD, SecF, and YajC form another heterotrimeric complex that can associate with the SecYEG complex...
  7. Taura T, Akiyama Y, Ito K. Genetic analysis of SecY: additional export-defective mutations and factors affecting their phenotypes. Mol Gen Genet. 1994;243:261-9 pubmed
    ..Overexpression of "yajC", located within the secD operon, suppressed secY-d1...
  8. Kato Y, Nishiyama K, Tokuda H. Depletion of SecDF-YajC causes a decrease in the level of SecG: implication for their functional interaction. FEBS Lett. 2003;550:114-8 pubmed
    SecA and an apparatus comprising SecYEG and SecDF-YajC complexes catalyze protein translocation across the Escherichia coli membrane...