yacG

Summary

Gene Symbol: yacG
Description: DNA gyrase inhibitor
Alias: ECK0101, JW5008
Species: Escherichia coli str. K-12 substr. MG1655
Products:     yacG

Top Publications

  1. Merlin C, McAteer S, Masters M. Tools for characterization of Escherichia coli genes of unknown function. J Bacteriol. 2002;184:4573-81 pubmed
    ..Replacements of yacF, yacG, yacH, yacK (cueO), yacL, ruvA, ruvB, yabB, and yabC made with the cassette were used to verify its properties.
  2. Ramelot T, Cort J, Yee A, Semesi A, Edwards A, Arrowsmith C, et al. NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins. Proteins. 2002;49:289-93 pubmed publisher
  3. Akiyama M, Horiuchi T, Sekiguchi M. Molecular cloning and nucleotide sequence of the mutT mutator of Escherichia coli that causes A:T to C:G transversion. Mol Gen Genet. 1987;206:9-16 pubmed
    ..The protein was overproduced when the mutT gene was placed under the control of the lac regulatory region on a multicopy runaway plasmid. The nucleotide sequence of the mutT gene was determined by the dideoxy method. ..
  4. Hare R, Walker S, Dorman T, Greene J, Guzman L, Kenney T, et al. Genetic footprinting in bacteria. J Bacteriol. 2001;183:1694-706 pubmed
    ..In addition, the ability of recombinant proteins to complement mutagenized hosts has been evaluated by genetic footprinting using a bacteriophage lambda transposon delivery system. ..
  5. Sengupta S, Nagaraja V. YacG from Escherichia coli is a specific endogenous inhibitor of DNA gyrase. Nucleic Acids Res. 2008;36:4310-6 pubmed publisher
    We assign a function for a small protein, YacG encoded by Escherichia coli genome. The NMR structure of YacG shows the presence of an unusual zinc-finger motif...