Gene Symbol: uidR
Description: transcriptional repressor
Alias: ECK1613, JW1610, gusR
Species: Escherichia coli str. K-12 substr. MG1655
Blanco C. Transcriptional and translational signals of the uidA gene in Escherichia coli K12. Mol Gen Genet. 1987;208:490-8 pubmed
The expression of uidA is negatively controlled by the products of the uidR and uxuR genes and is sensitive to catabolite repression...
Ramos J, Martínez Bueno M, Molina Henares A, Teran W, Watanabe K, Zhang X, et al
. The TetR family of transcriptional repressors. Microbiol Mol Biol Rev. 2005;69:326-56 pubmed
..Information related to the TetR family of regulators has been updated in a database that can be accessed at www.bactregulators.org. ..
Novel M, Novel G. Regulation of beta-glucuronidase synthesis in Escherichia coli K-12: constitutive mutants specifically derepressed for uidA expression. J Bacteriol. 1976;127:406-17 pubmed
..site uidO of the structural gene uidA; the second type of mutation (recessive) should affect a regulatory gene, uidR, operating through a negative control...
Novel M, Novel G. Regulation of beta-glucuronidase synthesis in Escherichia coli K-12: pleiotropic constitutive mutations affecting uxu and uidA expression. J Bacteriol. 1976;127:418-32 pubmed
..One of them was specific for uidA gene expression and was characterized as affecting either uidO or uidR sites...
Blanco C, Ritzenthaler P, Mata Gilsinger M. Negative dominant mutations of the uidR gene in Escherichia coli: genetic proof for a cooperative regulation of uidA expression. Genetics. 1986;112:173-82 pubmed
..gene involved in the hexuronide-hexuronate pathway in Escherichia coli K-12 and is under the dual control of the uidR and uxuR encoded repressors...
Blanco C, Ritzenthaler P, Mata Gilsinger M. Nucleotide sequence of a regulatory region of the uidA gene in Escherichia coli K12. Mol Gen Genet. 1985;199:101-5 pubmed
..A preliminary analysis of this sequence revealed the presence of numerous palindromic structures with some overlaps. ..
Blanco C, Mata Gilsinger M, Ritzenthaler P. The use of gene fusions to study the expression of uidR, a negative regulatory gene of Escherichia coli K-12. Gene. 1985;36:159-67 pubmed
The uidR regulatory gene of Escherichia coli codes for a repressor molecule that negatively controls the expression of the uidA gene...
Ritzenthaler P, Blanco C, Mata Gilsinger M. Interchangeability of repressors for the control of the uxu and uid operons in E. coli K12. Mol Gen Genet. 1983;191:263-70 pubmed
The uidA and uxuAB operons are each under the dual control of two repressor molecules: the uidR and uxuR encoded repressors negatively control the uidA operon whereas the uxuAB operon is regulated by the uxuR and exuR gene products...
Rodionov D, Mironov A, Rakhmaninova A, Gelfand M. Transcriptional regulation of transport and utilization systems for hexuronides, hexuronates and hexonates in gamma purple bacteria. Mol Microbiol. 2000;38:673-83 pubmed
..It includes all known and predicted members of the GntR, UxuR/ExuR, KdgR, UidR and IdnR regulons. Moreover, most members of these regulons seem to be under catabolite repression mediated by CRP...