Gene Symbol: tpiA
Description: triosephosphate isomerase
Species: Escherichia coli O157:H7 str. Sakai

Top Publications

  1. Mainfroid V, Goraj K, Rentier Delrue F, Houbrechts A, Loiseau A, Gohimont A, et al. Replacing the (beta alpha)-unit 8 of E.coli TIM with its chicken homologue leads to a stable and active hybrid enzyme. Protein Eng. 1993;6:893-900 pubmed
    ..Our kinetic studies show that the modification performed here leads to an active enzyme. The stability studies indicate that the stability of ETIM8CHI is comparable to that of the wild type TIM. ..
  2. Pichersky E, Gottlieb L, Hess J. Nucleotide sequence of the triose phosphate isomerase gene of Escherichia coli. Mol Gen Genet. 1984;195:314-20 pubmed
    ..To our knowledge, this is the first report of the sequence of a gene coding a glycolytic enzyme from a prokaryotic organism. ..
  3. Noble M, Zeelen J, Wierenga R, Mainfroid V, Goraj K, Gohimont A, et al. Structure of triosephosphate isomerase from Escherichia coli determined at 2.6 A resolution. Acta Crystallogr D Biol Crystallogr. 1993;49:403-17 pubmed
    ..In addition, TIM from E. coli shows peculiarities in its dimer interface, and in the packing of core residues within the beta-barrel. ..