torR

Summary

Gene Symbol: torR
Description: response regulator in two-component regulatory system with TorS
Alias: ECK0986, JW0980
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Simon G, Jourlin C, Ansaldi M, Pascal M, Chippaux M, Mejean V. Binding of the TorR regulator to cis-acting direct repeats activates tor operon expression. Mol Microbiol. 1995;17:971-80 pubmed
    ..The response regulator, TorR, has recently been identified as the regulatory protein that controls the expression of the torCAD operon in ..
  2. Toro Roman A, Wu T, Stock A. A common dimerization interface in bacterial response regulators KdpE and TorR. Protein Sci. 2005;14:3077-88 pubmed
    ..Here we report the X-ray crystal structures of the regulatory domains of response regulators TorR (1.8 A), Ca(2+)-bound KdpE (2.0 A), and Mg(2+)/BeF(3)(-)-bound KdpE (2...
  3. Simon G, Mejean V, Jourlin C, Chippaux M, Pascal M. The torR gene of Escherichia coli encodes a response regulator protein involved in the expression of the trimethylamine N-oxide reductase genes. J Bacteriol. 1995;177:275 pubmed
  4. Parkinson J. Signal transduction schemes of bacteria. Cell. 1993;73:857-71 pubmed
  5. Ansaldi M, Simon G, Lepelletier M, Mejean V. The TorR high-affinity binding site plays a key role in both torR autoregulation and torCAD operon expression in Escherichia coli. J Bacteriol. 2000;182:961-6 pubmed
    In the presence of trimethylamine N-oxide (TMAO), the TorS-TorR two-component regulatory system induces the torCAD operon, which encodes the TMAO respiratory system of Escherichia coli...
  6. Ansaldi M, Jourlin Castelli C, Lepelletier M, Theraulaz L, Mejean V. Rapid dephosphorylation of the TorR response regulator by the TorS unorthodox sensor in Escherichia coli. J Bacteriol. 2001;183:2691-5 pubmed
    ..the torCAD operon, encoding the trimethylamine N-oxide (TMAO) respiratory system, is tightly controlled by the TorS-TorR phosphorelay system in response to TMAO availability...
  7. Gao R, Tao Y, Stock A. System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids. Mol Microbiol. 2008;69:1358-72 pubmed publisher
    ..Weak hetero-pair interactions were also identified between several different RRs, suggesting potential cross-regulation between distinct pathways. ..
  8. Stock J, Stock A, Mottonen J. Signal transduction in bacteria. Nature. 1990;344:395-400 pubmed publisher
    ..This phosphotransfer network couples environmental signals to an array of response elements that control cell motility and regulate gene expression...
  9. Pao G, Saier M. Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. J Mol Evol. 1995;40:136-54 pubmed
    ..Sequence data were correlated with structure/function when such information was available.(ABSTRACT TRUNCATED AT 250 WORDS) ..

More Information

Publications12

  1. Simon G, Mejean V, Jourlin C, Chippaux M, Pascal M. The torR gene of Escherichia coli encodes a response regulator protein involved in the expression of the trimethylamine N-oxide reductase genes. J Bacteriol. 1994;176:5601-6 pubmed
    ..A torR insertion mutant unable to express the torA gene had previously been isolated...
  2. Parkinson J, Kofoid E. Communication modules in bacterial signaling proteins. Annu Rev Genet. 1992;26:71-112 pubmed
  3. Yuan Y, Jiaxin Q, Jing L, Hui L, Morigen M. [The effects of TorR protein on initiation of DNA replication in Escherichia coli]. Yi Chuan. 2015;37:302-8 pubmed publisher
    ..systems are associated with initiation of DNA replication and cell division, however, the effects of the TorS/TorR system on cell cycle and DNA replication remains unknown...