Gene Symbol: tamA
Description: translocation and assembly module for autotransporter export, outer membrane subunit
Alias: ECK4216, JW4179, yftM, ytfM
Species: Escherichia coli str. K-12 substr. MG1655
Stegmeier J, Glück A, Sukumaran S, Mäntele W, Andersen C. Characterisation of YtfM, a second member of the Omp85 family in Escherichia coli. Biol Chem. 2007;388:37-46 pubmed
..Interestingly, there exists a homologue to YaeT in E. coli and many proteobacteria, denoted YtfM, the function of which has not been described yet...
Casadio R, Fariselli P, Finocchiaro G, Martelli P. Fishing new proteins in the twilight zone of genomes: the test case of outer membrane proteins in Escherichia coli K12, Escherichia coli O157:H7, and other Gram-negative bacteria. Protein Sci. 2003;12:1158-68 pubmed
Burall L, Harro J, Li X, Lockatell C, Himpsl S, Hebel J, et al
. Proteus mirabilis genes that contribute to pathogenesis of urinary tract infection: identification of 25 signature-tagged mutants attenuated at least 100-fold. Infect Immun. 2004;72:2922-38 pubmed
Marani P, Wagner S, Baars L, Genevaux P, de Gier J, Nilsson I, et al
. New Escherichia coli outer membrane proteins identified through prediction and experimental verification. Protein Sci. 2006;15:884-9 pubmed
..Out of eight predicted outer membrane proteins, we have confirmed the outer membrane localization for five-YftM, YaiO, YfaZ, CsgF, and YliI--and also provide preliminary data indicating that a sixth--YfaL--may be an outer ..
Selkrig J, Mosbahi K, Webb C, Belousoff M, Perry A, Wells T, et al
. Discovery of an archetypal protein transport system in bacterial outer membranes. Nat Struct Mol Biol. 2012;19:506-10, S1 pubmed publisher
..Citrobacter rodentium, Salmonella enterica and Escherichia coli showed that it consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane of diverse bacterial species...
Robert V, Volokhina E, Senf F, Bos M, van Gelder P, Tommassen J. Assembly factor Omp85 recognizes its outer membrane protein substrates by a species-specific C-terminal motif. PLoS Biol. 2006;4:e377 pubmed
..coli outer membrane was accomplished after adapting its signature sequence. These results demonstrate that the Omp85 assembly machinery recognizes OMPs by virtue of their C-terminal signature sequence. ..
Gruss F, Z hringer F, Jakob R, Burmann B, Hiller S, Maier T. The structural basis of autotransporter translocation by TamA. Nat Struct Mol Biol. 2013;20:1318-20 pubmed publisher
b>TamA is an Escherichia coli Omp85 protein involved in autotransporter biogenesis. It comprises a 16-stranded transmembrane ?-barrel and three POTRA domains. The 2...