sapF

Summary

Gene Symbol: sapF
Description: antimicrobial peptide ABC transporter ATPase
Alias: ECK1285, JW1283
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Harms C, Domoto Y, Celik C, Rahe E, Stumpe S, Schmid R, et al. Identification of the ABC protein SapD as the subunit that confers ATP dependence to the K+-uptake systems Trk(H) and Trk(G) from Escherichia coli K-12. Microbiology. 2001;147:2991-3003 pubmed
    ..coli ATP dependence of Trk activity can be independent of Sap proteins. These data are interpreted to mean that Trk systems can interact with an ABC protein other than SapD...
  2. Sugiyama Y, Nakamura A, Matsumoto M, Kanbe A, Sakanaka M, Higashi K, et al. A Novel Putrescine Exporter SapBCDF of Escherichia coli. J Biol Chem. 2016;291:26343-26351 pubmed
    ..coli ?sapBCDF strain did not affect resistance to antimicrobial peptide LL-37. These results strongly suggest that the natural function of the SapBCDF proteins is the export of putrescine. ..
  3. Groisman E, Parra Lopez C, Salcedo M, Lipps C, Heffron F. Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Proc Natl Acad Sci U S A. 1992;89:11939-43 pubmed
    ..Our data indicate that the ability to resist the killing effect of host antimicrobial peptides is a virulence property and that several resistance mechanisms operate in S. typhimurium. ..
  4. Parra Lopez C, Baer M, Groisman E. Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium. EMBO J. 1993;12:4053-62 pubmed
    ..wild-type plasmid conferring resistance to protamine contained five open reading frames: sapA, sapB, sapC, sapD and sapF, organized in an operon structure and transcribed as a 5.3 kb mRNA...
  5. Stumpe -, Bakker -. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Arch Microbiol. 1997;167:126-36 pubmed
    ..Cells that cannot take up K+ rapidly remain metabolically compromised to such an extent that extracytoplasmic protease activity is not induced, leading to a prolonged susceptibility of the cells to the toxic peptide. ..
  6. Stumpe S, Bakker E. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Arch Microbiol. 1997;167:126-36 pubmed
    ..Cells that cannot take up K+ rapidly remain metabolically compromised to such an extent that extracytoplasmic protease activity is not induced, leading to a prolonged susceptibility of the cells to the toxic peptide. ..
  7. Parra Lopez C, Lin R, Aspedon A, Groisman E. A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium. EMBO J. 1994;13:3964-72 pubmed
    ..SapG may modulate the activities of SapABCDF and SapJ to mediate the transport of peptides and potassium. ..

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