rstA

Summary

Gene Symbol: rstA
Description: response regulator of RstAB two-component system
Alias: ECK1603, JW1600, urpT
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, Ishihama A. Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli. J Biol Chem. 2005;280:1448-56 pubmed
    ..CusS, HydH, RstB, YedV, and YfhK), and a total of 34 RRs, including putative RRs (BaeR, BasR, CreB, CusR, HydG, RstA, YedW, YfhA, YgeK, and YhjB), have been suggested to exist in Escherichia coli...
  2. Handford J, Ize B, Buchanan G, Butland G, Greenblatt J, Emili A, et al. Conserved network of proteins essential for bacterial viability. J Bacteriol. 2009;191:4732-49 pubmed publisher
    ..Each of the three conditional expression strains can be complemented by multicopy clones harboring the rstA gene, which encodes a two-component-system response regulator, strongly suggesting that these proteins are involved ..
  3. Roecklein B, Kuempel P. In vivo characterization of tus gene expression in Escherichia coli. Mol Microbiol. 1992;6:1655-61 pubmed
    ..We have also demonstrated that a minority of tus transcripts are initiated from an upstream region that contains two additional open reading frames. This readthrough transcription into tus is reduced in the presence of Tus protein. ..
  4. Minagawa S, Ogasawara H, Kato A, Yamamoto K, Eguchi Y, Oshima T, et al. Identification and molecular characterization of the Mg2+ stimulon of Escherichia coli. J Bacteriol. 2003;185:3696-702 pubmed
    ..Thus, we concluded that the phoPQ, mgrB, mgtA, hemL, nagA, rstAB, slyB, vboR, and yrbL genes make up the Mg(2+) stimulon in E. coli...
  5. Hirakawa H, Nishino K, Yamada J, Hirata T, Yamaguchi A. Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli. J Antimicrob Chemother. 2003;52:576-82 pubmed
    ..Thirteen response regulators out of 32 genes, namely baeR, cheY, cpxR, creB, evgA, fimZ, narL, ompR, rcsB, rstA, yedW, yehT and dcuR, conferred increased beta-lactam resistance...
  6. Eguchi Y, Okada T, Minagawa S, Oshima T, Mori H, Yamamoto K, et al. Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli. J Bacteriol. 2004;186:3006-14 pubmed
    ..coli resulted in enhanced expression of 13 PhoP/PhoQ-regulated genes, crcA, hemL, mgtA, ompT, phoP, phoQ, proP, rstA, rstB, slyB, ybjG, yrbL, and mgrB...
  7. Sermon J, Vanoirbeek K, De Spiegeleer P, Van Houdt R, Aertsen A, Michiels C. Unique stress response to the lactoperoxidase-thiocyanate enzyme system in Escherichia coli. Res Microbiol. 2005;156:225-32 pubmed
    ..Several of the induced genes or pathways may be involved in bacterial defense against the toxic effects of the lactoperoxidase-thiocyanate enzyme system. ..
  8. Campbell T, Ederer C, Allali Hassani A, Brown E. Isolation of the rstA gene as a multicopy suppressor of YjeE, an essential ATPase of unknown function in Escherichia coli. J Bacteriol. 2007;189:3318-21 pubmed
    ..Using a genomic library, we have identified rstA as a multicopy suppressor of a conditional yjeE deletion strain...
  9. Ogasawara H, Hasegawa A, Kanda E, Miki T, Yamamoto K, Ishihama A. Genomic SELEX search for target promoters under the control of the PhoQP-RstBA signal relay cascade. J Bacteriol. 2007;189:4791-9 pubmed
    ..In order to identify the network of transcription regulation downstream of RstBA, we isolated a set of RstA-binding sequences from the E. coli genome by using the genomic SELEX system...

More Information

Publications11

  1. Gao R, Tao Y, Stock A. System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids. Mol Microbiol. 2008;69:1358-72 pubmed publisher
    ..Weak hetero-pair interactions were also identified between several different RRs, suggesting potential cross-regulation between distinct pathways. ..
  2. Msadek T. Grasping at shadows: revealing the elusive nature of essential genes. J Bacteriol. 2009;191:4701-4 pubmed publisher