rsmE

Summary

Gene Symbol: rsmE
Description: 16S rRNA m(3)U1498 methyltransferase, SAM-dependent
Alias: ECK2941, JW2913, yggJ
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. Forouhar F, Shen J, Xiao R, Acton T, Montelione G, Tong L. Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot. Proteins. 2003;53:329-32 pubmed publisher
  2. Gushima H, Yasuda S, Soeda E, Yokota M, Kondo M, Kimura A. Complete nucleotide sequence of the E. coli glutathione synthetase gsh-II. Nucleic Acids Res. 1984;12:9299-307 pubmed
    ..These structural features found in the non-coding regions have suggested to be involved in regulatory functions for the gsh-II gene expression. ..
  3. Basturea G, Rudd K, Deutscher M. Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family. RNA. 2006;12:426-34 pubmed
    ..Here, we show that the protein encoded by yggJ, a member of the uncharacterized DUF558 protein family of predicted alpha/beta (trefoil) knot methyltransferases is ..
  4. Basturea G, Deutscher M. Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA. 2007;13:1969-76 pubmed
    ..One of these enzymes, RsmE, was recently identified and shown to specifically methylate U1498...
  5. Zhang H, Wan H, Gao Z, Wei Y, Wang W, Liu G, et al. Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m³U1498) from crystal and solution structures. J Mol Biol. 2012;423:576-89 pubmed publisher
    b>RsmE is the founding member of a new RNA methyltransferase (MTase) family responsible for methylation of U1498 in 16S ribosomal RNA in Escherichia coli...
  6. Jekel M, Wackernagel W. Location of the endA gene coding for endonuclease I on the physical map of the Escherichia coli K-12 chromosome. J Bacteriol. 1994;176:1550-1 pubmed
  7. Das G, Thotala D, Kapoor S, Karunanithi S, Thakur S, Singh N, et al. Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli. EMBO J. 2008;27:840-51 pubmed publisher
    ..Targeted mutations in the methyltransferase genes have revealed a connection between the rRNA modifications and the fundamental process of the initiator tRNA selection by the ribosome. ..