Gene Symbol: rsmE
Description: 16S rRNA m(3)U1498 methyltransferase, SAM-dependent
Alias: ECK2941, JW2913, yggJ
Species: Escherichia coli str. K-12 substr. MG1655
Forouhar F, Shen J, Xiao R, Acton T, Montelione G, Tong L. Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot. Proteins. 2003;53:329-32 pubmed publisher
Gushima H, Yasuda S, Soeda E, Yokota M, Kondo M, Kimura A. Complete nucleotide sequence of the E. coli glutathione synthetase gsh-II. Nucleic Acids Res. 1984;12:9299-307 pubmed
..These structural features found in the non-coding regions have suggested to be involved in regulatory functions for the gsh-II gene expression. ..
Basturea G, Rudd K, Deutscher M. Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family. RNA. 2006;12:426-34 pubmed
..Here, we show that the protein encoded by yggJ, a member of the uncharacterized DUF558 protein family of predicted alpha/beta (trefoil) knot methyltransferases is ..
Basturea G, Deutscher M. Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA. 2007;13:1969-76 pubmed
..One of these enzymes, RsmE, was recently identified and shown to specifically methylate U1498...
Zhang H, Wan H, Gao Z, Wei Y, Wang W, Liu G, et al
. Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m³U1498) from crystal and solution structures. J Mol Biol. 2012;423:576-89 pubmed publisher
b>RsmE is the founding member of a new RNA methyltransferase (MTase) family responsible for methylation of U1498 in 16S ribosomal RNA in Escherichia coli...
Jekel M, Wackernagel W. Location of the endA gene coding for endonuclease I on the physical map of the Escherichia coli K-12 chromosome. J Bacteriol. 1994;176:1550-1 pubmed
Das G, Thotala D, Kapoor S, Karunanithi S, Thakur S, Singh N, et al
. Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli. EMBO J. 2008;27:840-51 pubmed publisher
..Targeted mutations in the methyltransferase genes have revealed a connection between the rRNA modifications and the fundamental process of the initiator tRNA selection by the ribosome. ..